Valsartan impurity 7 CAS 914465-68-2
| CAS No. | 914465-68-2 |
| Molecular Formula | C19H21N5O |
| Molecular Weight | 335.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Valsartan impurity 7.
Valsartan impurity 7 (CAS 914465-68-2) is a certified pharmaceutical impurity reference standard with the molecular formula C19H21N5O and a molecular weight of 335.40 g/mol.
Structurally, Valsartan impurity 7 (C19H21N5O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 335.40 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Valsartan impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H21N5O |
| Molecular Weight | 335.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 5 |
Related Valsartan Standards
- Valsartan Impurity 100 (CAS CATO-C4X-1057100)
- Valsartan Impurity 109 (CAS 2407652-86-0)
- Valsartan Impurity 20 (CAS CATO-C4X-105720)
- Valsartan Impurity 87 (CAS 196707-31-0)
- Valsartan Impurity 37 (CAS CATO-C4X-105737)
- Valsartan Impurity 127 (CAS CATO-C4X-1057127)
- Valsartan Impurity 30 (CAS 209911-63-7)
- Valsartan Impurity 103 (CAS 1391068-02-2)
Recommended Standards
- Roxatidine Impurity 79 (CAS CATO-C4X-121379)
- 898763-91-2 Ethyl 3-{4-[(2,5-dihydro-1H-pyrrol-1-yl)methyl]benzoyl}benzoate DTXSID90643021 (CAS 898763-91-2)
- Alcaftadine Impurity 2 (CAS CATO-C4X-17952)
- Venadaparib Impurity 96 (CAS 33048-50-9)
- Lamotrigine Impurity 14 (CAS CATO-C4X-167214)
- Leuprorelin EP Impurity G Trifluoroacetic acid (CAS 112710-57-3(free base))
- Olodaterol Impurity 16 (CAS CATO-C4X-194316)
- 2-Cyclopropoxy-1-isopropyl-4-methylbenzene (CAS 1243390-88-6)
- 2-(4-Chloro-2-fluorophenyl)-2,2-difluoroethan-1-ol (CAS 1824017-29-9)
- (1S,3S)-3-methoxycyclohexane-1-carboxylic acid (CAS 2231666-50-3)
- 6-((6-Methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptane (CAS 2306275-33-0)
- Methyl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate (CAS 40349-50-6)
- 3-(Difluoromethyl)-5-nitro-2-(trifluoromethyl)pyridin-4-amine (CAS 1806890-25-4)
- Semaglutide impurity 258 (CAS CATO-C4X-2226258)
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