Belumosudil Impurity N7 CAS 911419-33-5
| CAS No. | 911419-33-5 |
| Molecular Formula | C23H17N5O2 |
| Molecular Weight | 395.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Belumosudil Impurity N7 (CAS 911419-33-5, C23H17N5O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Belumosudil Impurity N7 (C23H17N5O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 18.0, corresponding to approximately 18 ring(s) or double-bond equivalent(s). With a molecular weight of 395.41 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H17N5O2 |
| Molecular Weight | 395.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 5 |
Related Belumosudil Standards
- Belumosudil Impurity 53 (CAS CATO-C4X-298853)
- Belumosudil Impurity 40 (CAS 2988752-00-5)
- Belumosudil Impurity 50 (CAS CATO-C4X-298850)
- Belumosudil Impurity 45 (CAS CATO-C4X-298845)
- Belumosudil Impurity 37 (CAS CATO-C4X-298837)
- Belumosudil Impurity 35 (CAS CATO-C4X-298835)
- Belumosudil Impurity 43 (CAS 2121561-41-7)
- Belumosudil Impurity 33 (CAS 2121561-37-1)
Recommended Standards
- Z-Gly-Trp-OH (C-1925.0005) (CAS 3392-19-6)
- N7-benzyl-N4-(3-ethynylphenyl)-6-nitroquinazoline-4,7-diamine (CAS CATO-C3D-262421)
- tert-Butyl ((diphenylphosphoryl)methyl)sulfonylcarbamate (CAS 410529-86-1)
- Rivaroxaban impurity 176 (CAS CATO-C4X-1090176)
- Carglumic Acid impurity 12 (CAS CATO-C4X-207912)
- Biotin EP Impurity B (CAS 57671-79-1)
- Pregabalin Impurity PD 0224378 (CAS CATO-C4X-13124)
- 3-Bromo-4-(chloromethyl)-6-(difluoromethyl)pyridin-2-amine (CAS 1804694-04-9)
- 6-Chloro-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxylic acid, 97% (CAS 959277-17-9)
- 6,6'-(Ethene-1,2-diyl)bis(3-isothiocyanatobenzenesulfonic acid) (CAS 53005-05-3)
- 6-(tert-Butyl)indoline-2,3-dione (CAS 388628-10-2)
- Ubidecarenone impurity 21 (CAS CATO-C4X-137621)
- 3-(4-Hydroxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 879996-57-3)
- Liraglutide Impurity 22 (CAS 536721-25-2)
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