1H-Benzimidazole-4-carboxamide, 2-[(2S)-2-methyl-2-pyrrolidinyl]-, dihydrochloride CAS 912445-36-4
| CAS No. | 912445-36-4 |
| Molecular Formula | C13H16N4O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1H-Benzimidazole-4-carboxamide, 2-[(2S)-2-methyl-2-pyrrolidinyl]-, dihydrochloride (CAS 912445-36-4), molecular formula C13H16N4OHCl and molecular weight 280.76 g/mol, is a CATO reference standard with documented purity and traceability.
1H-Benzimidazole-4-carboxamide, 2-[(2S)-2-methyl-2-pyrrolidinyl]-, dihydrochloride (C13H16N4OHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H16N4O 2*HCl |
| Molecular Weight | 280.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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- (E)-3-(O-tolyl)acrylaldehyde (CAS 93614-78-9)
- Dapagliflozin Impurity 75 (CAS CATO-C4X-113875)
- A-18-F-NH2; Morphine Modulating Neuropeptide (CAS 99588-52-0)
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