Dapagliflozin Impurity 75 CAS CATO-C4X-113875
| CAS No. | CATO-C4X-113875 |
| Molecular Formula | C15H14BrIO |
| Molecular Weight | 417.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dapagliflozin Impurity 75 is closely related to a hydroxyl group, an ether linkage, bromine/iodine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Dapagliflozin Impurity 75 (CAS CATO-C4X-113875) is a certified pharmaceutical impurity reference standard with the molecular formula C15H14BrIO and a molecular weight of 417.08 g/mol.
Owing to a hydroxyl group, an ether linkage, bromine/iodine substitution, a polycyclic aromatic system, Dapagliflozin Impurity 75 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 417.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dapagliflozin Impurity 75 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H14BrIO |
| Molecular Weight | 417.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br/I-containing |
Related Dapagliflozin Standards
- Dapagliflozin-13C6 (glucitol-13C6) (CAS CATO-C4X-113859)
- Dapagliflozin-D5 (CAS 1204219-80-6)
- Dapagliflozin Impurity 171 (CAS CATO-C4X-1138171)
- Dapagliflozin Impurity 20 (CAS 2169998-23-4)
- Dapagliflozin Impurity 37 (CAS 946525-39-9)
- Dapagliflozin Impurity 120 (CAS 1204220-63-2)
- Dapagliflozin Impurity 109 (CAS 2088749-74-8)
- Dapagliflozin Impurity 110 (CAS CATO-C4X-1138110)
Recommended Standards
- 3-benzyl-5-(3-chlorophenyl)-6-methyl-2-sulfanyl-3H,4H-thieno[2,3-d]pyrimidin-4-one (CAS 744227-39-2)
- 10-(3,5-Dibromophenyl)-10H-phenoxazine (CAS 1313412-21-3)
- [1-(3,4-Dichlorophenyl)-1H-1,2,3-triazol-4-yl]methyl 3,4-dichlorobenzoate (CAS 338756-77-7)
- 4-(Methylthio)-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)butanoic acid (CAS 351436-89-0)
- Erlotinib Impurity 108 (CAS 311-28-4)
- Benzylpenicillin Impurity 71 (CAS CATO-C4X-189971)
- Omeprazole Impurity 26 (CAS 2572712-50-4)
- (3-Methylpyridin-4-yl)methanamine dihydrochloride (CAS 85127-50-0)
- 1-(3-(Trifluoromethyl)phenyl)pyrrolidin-2-one (CAS 38348-84-4)
- 4-Hydroxy-5-methylquinoline-2-carboxylic acid (CAS 36303-31-8)
- tert-Butyl 1-(3-bromo-5-fluoropyridin-4-yl)piperidine-4-carboxylate (CAS 1613193-36-4)
- 6-Bromo-N-methoxy-N-methylnicotinamide (CAS 149806-05-3)
- Butopyronoxyl (CAS 532-34-3)
- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
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