5-Chloro-3-hydroxy-2-methylpyridine CAS 91420-23-4
| CAS No. | 91420-23-4 |
| Molecular Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-3-hydroxy-2-methylpyridine.
5-Chloro-3-hydroxy-2-methylpyridine (CAS 91420-23-4), molecular formula C6H6ClNO and molecular weight 143.57 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 5-Chloro-3-hydroxy-2-methylpyridine is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 143.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-3-hydroxy-2-methylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-6-methylpyridin-2-ol (CAS 103997-23-5)
- N-(3-Chloro-phenyl)hydroxylamine (CAS 10468-17-4)
- (5-Chloro pyrazin-2-yl) Methanamine (CAS 1060814-53-0)
- 4-Chloro-3-methylpyridine 1-Oxide (CAS 1073-34-3)
- 2-Chloro-3-hydrazinylpyridine (CAS 117087-45-3)
- 5-Chloro-2-methylpyridin-4(1H)-one (CAS 1196157-19-3)
- 2-Chloro-1-(1H-pyrrol-3-yl)ethanone (CAS 122450-28-6)
- 3-Chloro-2-methylpyridin-4-ol (CAS 1227499-23-1)
Recommended Standards
- 5-Chloro-3,4-diaminopyridine (CAS 929074-42-0)
- 5-Chloro-3-methylpyridin-2-ol (CAS 58498-61-6)
- 5-Chloro-2-methylpyrimidin-4-amine (CAS 438249-95-7)
- 5-Chloro-4-methylpyridin-2-ol (CAS 886364-92-7)
- 2,6-Dicyclopentylaniline (CAS 67330-67-0)
- 8,8-Dimethyl-7-oxo-2-azaspiro[3.5]non-5-ene-6-carbonitrile hydrochloride (CAS 2758304-16-2)
- 5-Acetamido-2,4,6-triiodoisophthaloyl Dichloride (CAS 31122-75-5)
- 3-Methyl-4-(pentyloxy)benzenesulfonamide (CAS 1094491-12-9)
- Perfluorophenyl 2,4,6-triisopropylbenzenesulfonate (CAS 886361-20-2)
- 2,5-Dichloro-3-(difluoromethyl)pyridin-4-ol (CAS 1805989-96-1)
- Prop-2-en-1-yl N-[2-(4-chlorophenyl)quinolin-4-yl]carbamate (CAS 338401-44-8)
- (3-(3-Chlorophenyl)isoxazol-5-yl)methanol (CAS 101862-42-4)
- 3-(2,3-Dihydro-1-benzofuran-7-yl)propanoic acid (CAS 1251468-51-5)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
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