5-(4-Fluorophenyl)picolinonitrile CAS 914349-75-0
| CAS No. | 914349-75-0 |
| Molecular Formula | C12H7FN2 |
| Molecular Weight | 198.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-(4-Fluorophenyl)picolinonitrile (CAS 914349-75-0), a certified reference material (molecular formula C12H7FN2, MW 198.20 g/mol) for analytical method development and quality control.
The molecular framework of 5-(4-Fluorophenyl)picolinonitrile (C12H7FN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 5-(4-Fluorophenyl)picolinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7FN2 |
| Molecular Weight | 198.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 5-(2-Fluorophenyl)nicotinonitrile (CAS 1214334-11-8)
- 2-(4-Fluorophenyl)pyridine-3-carbonitrile (CAS 1214335-17-7)
- 6-(3-Fluorophenyl)nicotinonitrile (CAS 1214340-27-8)
- 3-(4-Fluorophenyl)pyridine-2-carbonitrile (CAS 1214340-31-4)
- 5-(3-Fluorophenyl)nicotinonitrile (CAS 1214373-90-6)
- 4-(2-Fluorophenyl)picolinonitrile (CAS 1219454-74-6)
- 5-(4-Fluorophenyl)nicotinonitrile (CAS 154237-18-0)
- 3-(2-Fluorophenyl)isonicotinonitrile (CAS 868944-77-8)
Recommended Standards
- 4-Mercaptophthalic acid (CAS 82520-79-4)
- 5-Aminobenzo[d]isothiazol-3(2H)-one 1,1-Dioxide (CAS 22094-61-7)
- 4-Mercaptoisophthalic acid (CAS 214341-16-9)
- 5-Fluoro-2-(4-morpholinyl)-4-pyrimidinylamine (CAS 312928-75-9)
- 2-(Quinolin-4-yl)cyclopropan-1-amine (CAS 1493128-10-1)
- 1-Ethyl-2-mercapto-5,7-dimethylpyrido[2,3-d]-pyrimidin-4(1H)-one (CAS 937599-68-3)
- 3,4-Dichloro-2-(difluoromethoxy)aniline (CAS 1805123-94-7)
- 2-[(3-Fluorobenzyl)oxy]-3-methoxybenzoyl chloride (CAS 1160250-80-5)
- 6-Amino-5-hydroxy-3,3-dimethylindolin-2-one (CAS 1369362-33-3)
- 2-Fluoro-4-(1-methyl-1H-pyrazol-4-yl)benzoic acid (CAS 1178280-85-7)
- 3,4-Diamino-2-methylbenzonitrile (CAS 1481633-77-5)
- 2-(2-Amino-4-hydroxypyrimidin-5-yl)-2-methylpropanoic acid (CAS 1184920-53-3)
- Perindopril Impurity 85 (CAS CATO-C4X-125285)
- Tirzepatide Impurity 22 X TFA Salt (CAS CATO-C4X-324022)
Why CATO?
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