3-(2-Chloro-5-fluoro-phenyl)-3-oxo-propionitrile CAS 914636-71-8
| CAS No. | 914636-71-8 |
| Molecular Formula | C9H5ClFNO |
| Molecular Weight | 197.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 3-(2-Chloro-5-fluoro-phenyl)-3-oxo-propionitrile (CAS 914636-71-8), a certified reference material (molecular formula C9H5ClFNO, MW 197.59 g/mol) for analytical method development and quality control.
The molecular framework of 3-(2-Chloro-5-fluoro-phenyl)-3-oxo-propionitrile (C9H5ClFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 3-(2-Chloro-5-fluoro-phenyl)-3-oxo-propionitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5ClFNO |
| Molecular Weight | 197.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-8-fluoroquinolin-4(1H)-one (CAS 1019016-37-5)
- 6-Chloro-8-fluoroquinolin-4-ol (CAS 1019016-45-5)
- 7-Chloro-8-fluoroquinolin-4(1H)-one (CAS 1019016-52-4)
- 7-Chloro-6-fluoroquinolin-4(1H)-one (CAS 106024-91-3)
- 2-Chloro-5-(4-fluorophenyl)oxazole (CAS 1060816-27-4)
- 6-Chloro-7-fluoroquinolin-4(1H)-one (CAS 1065092-30-9)
- 8-Chloro-5-fluoroquinolin-4(1H)-one (CAS 1065092-32-1)
- 8-Chloro-7-fluoroquinolin-4(1H)-one (CAS 1065092-33-2)
Recommended Standards
- 3-(2-Chloro-4-fluorophenyl)-3-oxopropanenitrile (CAS 914636-68-3)
- 3-(2-Chloro-6-fluorophenyl)-3-oxopropanenitrile (CAS 267881-03-8)
- 2-Chloro-5-fluoro-1H-indole-3-carbaldehyde (CAS 535925-49-6)
- 3-(3-chloro-4-fluorophenyl)-3-oxopropanenitrile (CAS 267880-79-5)
- Methyl 2-(2-((tert-butoxycarbonyl)amino)ethyl)oxazole-4-carboxylate (CAS 871726-03-3)
- N-Hydroxypyrimidine-5-carbimidoyl chloride (CAS 1009562-97-3)
- 799812-75-2 (2S,3R,4E)-2-Azaniumyl-3-hydroxyicos-4-en-1-yl hydrogen phosphate DTXSID50677069 (CAS 799812-75-2)
- Ethyl 4-(2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamido)benzoate (CAS 1040682-29-8)
- n-(4-(Methylsulfonamido)phenyl)acetamide (CAS 77167-09-0)
- 2-(3-Chlorobenzyl)-4-((2,4-dichlorobenzyl)oxy)quinazoline (CAS 861208-37-9)
- N-1,3-Benzoxazol-2-ylsulfuric diamide (CAS 136810-65-6)
- Amiflamine hydrogentartrate (CAS 84257-38-5)
- 4-Amino-2-(butylthio)-6-(methylthio)pyrimidine-5-carbonitrile (CAS 647832-47-1)
- Semaglutide Impurity 176 (CAS CATO-C4X-2226176)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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