3-(Difluoromethoxy)-4-fluorobenzonitrile 916210-09-8 CAS 916210-09-8
| CAS No. | 916210-09-8 |
| Molecular Formula | C8H4F3NO |
| Molecular Weight | 187.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-(Difluoromethoxy)-4-fluorobenzonitrile 916210-09-8 (CAS 916210-09-8), a certified reference material (molecular formula C8H4F3NO, MW 187.12 g/mol) for analytical method development and quality control.
Based on its molecular formula C8H4F3NO, 3-(Difluoromethoxy)-4-fluorobenzonitrile 916210-09-8 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 187.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(Difluoromethoxy)-4-fluorobenzonitrile 916210-09-8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4F3NO |
| Molecular Weight | 187.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethoxy Standards
- 2-(Difluoromethoxy)-5-fluorobenzonitrile (CAS 1017778-48-1)
- 4-(Difluoromethoxy)-2-fluorobenzonitrile (CAS 1017779-49-5)
- 5-(difluoromethoxy)-2-fluorobenzonitrile (CAS 1261499-62-0)
- 3-(Difluoromethoxy)-5-fluorobenzonitrile (CAS 1261674-63-8)
- 2-(Difluoromethoxy)-4-fluorobenzonitrile (CAS 933772-76-0)
- 2-(Difluoromethoxy)-6-fluorobenzonitrile (CAS 221202-14-8)
- 4-(Difluoromethoxy)-3-fluorobenzonitrile (CAS 954388-59-1)
- 6-(Difluoromethoxy)-4-methylnicotinaldehyde (CAS 1079352-17-2)
Recommended Standards
- Selenopheno[3,2-b]thiophene (CAS 20503-37-1)
- Sorafenib Impurity 20 (CAS 329-01-1)
- o-(Trifluoromethyl)homoserine (CAS 2055866-42-5)
- Apalutamide Impurity 14 (CAS 573762-62-6)
- 5-Amino-6-methoxynicotinic acid (CAS 1393568-65-4)
- 3-(1-ethyl-1H-pyrazol-4-yl)thiomorpholine dihydrochloride (CAS 1798709-10-0)
- 2-Amino-2-(2-(trifluoromethyl)phenyl)acetamide (CAS 959139-88-9)
- 3-[(4-ethylphenoxy)methyl]-4-methoxybenzaldehyde (CAS 438531-34-1)
- 4-Allyl-2-fluoro-1-methoxybenzene (CAS 222422-50-6)
- (2S,4R)-4-Fluoropyrrolidine-2-carboxamide (CAS 851509-26-7)
- 7'-Nitro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinolin]-1'-one (CAS 2568928-18-5)
- n-Formyl-o-isopropylhomoserine (CAS 1500649-99-9)
- Perindopril Impurity N1 (CAS 108507-42-2)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com