Siponimod Impurity 3 CAS 916806-97-8
| CAS No. | 916806-97-8 |
| Molecular Formula | C14H15F3O2 |
| Molecular Weight | 272.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Siponimod Impurity 3 (C14H15F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Siponimod Impurity 3 (CAS 916806-97-8) is a certified pharmaceutical impurity reference standard with the molecular formula C14H15F3O2 and a molecular weight of 272.26 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Siponimod Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H15F3O2 |
| Molecular Weight | 272.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Siponimod Standards
- Siponimod impurity 16 (CAS CATO-C4X-247216)
- Siponimod Impurity 10 (CAS CATO-C4X-247210)
- Siponimod Impurity 8 (CAS CATO-C4X-24728)
- Siponimod Impurity 11 (CAS 2474774-17-7)
- Siponimod Impurity 5 (CAS 957205-23-1)
- Siponimod Impurity 2 (CAS 957202-29-8)
- Siponimod impurity 24 (CAS CATO-C4X-247224)
- Siponimod Impurity 9 (CAS 2746387-13-1)
Recommended Standards
- Proxyphylline Impurity 8 (CAS CATO-C4X-24408)
- Ethacridine Lactate Impurity 11 (CAS CATO-C4X-260911)
- Diprophylline Impurity 6 (CAS CATO-C4X-24406)
- Ethacridine Lactate Impurity 32 (CAS 62327-30-4)
- Prednisone Impurity 6 (CAS CATO-C4X-16946)
- Minoxidil Impurity 64 (CAS CATO-C4X-170064)
- Esomeprazole Impurity 94 (CAS 91219-89-5)
- 2-(1H-Pyrrol-1-yl)-6-(trifluoromethyl)aniline (CAS 866042-07-1)
- 1-methyl-2-oxidanylidene-pyridine-4-carboxylic acid 1-methyl-2-oxo-4-pyridinecarboxylic acid 33972-97-3 A822026 (CAS 33972-97-3)
- 4-(Dimethylamino)-6-phenyl-2-(pyridin-2-yl)pyrimidine-5-carbonitrile (CAS 320418-16-4)
- 2-(2-Hydroxybicyclo[2.2.1]heptan-2-yl)-2-phenylacetic acid (CAS 24183-94-6)
- 2,2,2-Trifluoro-1-(6-nitro-3-indolyl)ethanone (CAS 676476-90-7)
- Spiro[4.5]decan-7-amine hydrochloride (CAS 62439-56-9)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com