Siponimod impurity 24 CAS CATO-C4X-247224
| CAS No. | CATO-C4X-247224 |
| Molecular Formula | C14H16F3NO2 |
| Molecular Weight | 287.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Siponimod impurity 24 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Siponimod impurity 24 (CAS CATO-C4X-247224) is a certified pharmaceutical impurity reference standard with the molecular formula C14H16F3NO2 and a molecular weight of 287.28 g/mol.
The molecular framework of Siponimod impurity 24 (C14H16F3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H16F3NO2 |
| Molecular Weight | 287.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Siponimod Standards
- Siponimod Impurity 2 (CAS 957202-29-8)
- Siponimod Impurity 6 (CAS 2305339-74-4)
- Siponimod impurity 18 (CAS CATO-C4X-247218)
- Siponimod Impurity 4 (CAS 1589558-70-2)
- Siponimod Impurity 3 (CAS 916806-97-8)
- Siponimod impurity 16 (CAS CATO-C4X-247216)
- Siponimod Impurity 31 (CAS CATO-C4X-247231)
- Siponimod Impurity 10 (CAS CATO-C4X-247210)
Recommended Standards
- Ponatinib Impurity 57 (CAS CATO-C4X-226957)
- Methyl 2-((4-(difluoromethyl)-2-methyl-2H-pyrazolo[3,4-b]pyridin-6-yl)thio)acetate (CAS 1018047-37-4)
- Nafamostat impurity 115 (CAS CATO-C4X-1332115)
- 2-((4-(Difluoromethyl)-2-ethyl-2h-pyrazolo[3,4-b]pyridin-6-yl)thio)acetic acid (CAS 1018166-37-4)
- Dequalinium Impurity 5 (CAS 51309-10-5)
- Phosphoramidite Impurity 28 (CAS 2005449-47-6)
- Imatinib Impurity 64 (CAS 1356565-47-3)
- 9-((2-(Diethylamino)ethyl)thio)acridin-3-amine (CAS 129821-07-4)
- 2-Bromo-3-(2,6-dimethoxyphenyl)-1-propene (CAS 951891-27-3)
- ((1r,2s,4s)-7-Oxabicyclo[2.2.1]heptan-2-yl)methanamine (CAS 1486473-03-3)
- 4-(2-Methoxy-5-methylphenyl)butan-1-amine (CAS 1216105-06-4)
- bis-(2-thienyl) methane (CAS 4341-34-8)
- Gadopiclenol Impurity 2 (CAS 311772-46-0)
- CBP501 Affinity Peptide trifluoroacetate salt (CAS 1351804-17-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com