Sertraline Impurity 19 CAS 91797-58-9
| CAS No. | 91797-58-9 |
| Molecular Formula | C16H15Cl2N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Sertraline Impurity 19.
As a process- or degradation-related impurity, Sertraline Impurity 19 (CAS 91797-58-9, C16H15Cl2NHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Sertraline Impurity 19 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 328.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sertraline Impurity 19 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H15Cl2N HCl |
| Molecular Weight | 328.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Sertraline Standards
- Sertraline - Impurity C (Freebase) (CAS 107538-91-0)
- Sertraline Acetamide (CAS 1097616-52-8)
- Sertraline Carbamoyl Glucuronide (CAS 119733-44-7)
- Sertraline Impurity 26 (CAS 1198115-10-4（free base）)
- Sertraline RC 11 (CAS 1217630-23-3)
- Sertraline-d3 Hydrochloride (CAS 1217741-83-7)
- Sertraline Impurity 50 HCl (CAS 122873-20-5 (free base))
- Sertraline EP Impurity F Enantiomer (CAS 124379-29-9)
Recommended Standards
- Methotrexate Impurity 72 (CAS CATO-C4X-115472)
- Sunitinib Impurity 51 (CAS 253870-02-9)
- Landiolol Impurity 63 (CAS CATO-C4X-262162)
- Methyl Acetate-d6 (CAS 32113-85-2)
- (2S,3R)-N-(tert-Butyloxycarbonyl)-3-methyl-pyroglutaminol (CAS 910548-24-2)
- 2-(4-Fluorobenzoyl)-5-methylpyridine (CAS 497854-91-8)
- 8-Bromo-2-methylquinazolin-4-amine (CAS 1279724-72-9)
- 2-(2-Bromophenyl)-1,1-bi(cyclopropyl) (CAS 599197-56-5)
- N2-Methyl-1H-benzo[d]imidazole-2,5-diamine (CAS 832102-62-2)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com