Nefopam Impurity 8 CAS 918306-38-4
| CAS No. | 918306-38-4 |
| Molecular Formula | C11H13NO4 |
| Molecular Weight | 223.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nefopam Impurity 8.
CATO supplies Nefopam Impurity 8 (CAS 918306-38-4), a pharmacopoeial impurity reference standard (molecular formula C11H13NO4, MW 223.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Nefopam Impurity 8 (C11H13NO4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nefopam Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H13NO4 |
| Molecular Weight | 223.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Nefopam Standards
- Nefopam Impurity 11 (CAS CATO-C4X-283711)
- Nefopam Impurity 1 (CAS CATO-C4X-28381)
- Nefopam Impurity 4 (CAS 32557-55-4)
- Nefopam impurity 22 (CAS CATO-C4X-283722)
- Nefopam impurity 23 (CAS CATO-C4X-283723)
- Nefopam Impurity 7 (CAS 22103-85-1)
- Nefopam Impurity 34 (CAS CATO-C4X-283734)
- (S)-(+)-Nefopam (CAS 110011-82-0)
Recommended Standards
- Bambuterol Impurity 2 (CAS CATO-C4X-27462)
- Belumosudil Impurity 31 (CAS 954269-05-7)
- Acetazolamide EP Impurity E (CAS 827026-60-8)
- Bentranil (CAS 1022-46-4)
- Lafutidine impurity 16 (CAS 129622-98-6)
- Relebactam Impurity 75 (CAS CATO-C4X-214475)
- Bumetanide Impurity 108 (CAS CATO-C4X-1986108)
- N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-(2-(dimethylamino)ethoxy)benzamide (CAS 1853-99-2)
- tert-butyl 4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole-1-carboxylate (CAS 1256359-94-0)
- 3,4-Dimethyl-5-nitrobenzene-1-sulfonyl chloride (CAS 873208-62-9)
- (2-(Methylthio)phenyl)(pyridin-2-yl)methanol (CAS 1443343-73-4)
- 898763-22-9 (3,4-Dimethylphenyl){3-[(thiomorpholin-4-yl)methyl]phenyl}methanone DTXSID40643374 (CAS 898763-22-9)
- N-(1-((3R,5R,7R)-Adamantan-1-yl)ethyl)acetamide (CAS 180271-41-4)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com