Nefopam Impurity 7 CAS 22103-85-1
| CAS No. | 22103-85-1 |
| Molecular Formula | C14H9ClO2 |
| Molecular Weight | 244.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Nefopam Impurity 7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Nefopam Impurity 7 (CAS 22103-85-1, C14H9ClO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system, Nefopam Impurity 7 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 244.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H9ClO2 |
| Molecular Weight | 244.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
Related Nefopam Standards
Recommended Standards
- Sodium Cromoglicate Impurity 12 (CAS CATO-C4X-201112)
- 2-(4-Chlorophenyl)-1H-1,3-benzodiazol-1-ol (CAS 10066-08-7)
- Diltiazem Impurity 31 (CAS CATO-C4X-136831)
- 6-Chloro-2-phenyl-1H-1,3-benzodiazol-1-ol (CAS 10066-09-8)
- Piribedil Impurity 5 (CAS CATO-C4X-28135)
- Clevidipine butyrate Impurity 15 (CAS 1801167-49-6)
- Pomalidomide Impurity 58 (CAS 18658-36-1)
- 3-Amino-N-(benzo[d][1,3]dioxol-5-yl)-4-methylbenzamide (CAS 1018271-87-8)
- 2-((Methylsulfonyl)methyl)pyrrolidine (CAS 1342475-48-2)
- 3-(Methylsulfanyl)-5-[2-(methylsulfanyl)phenyl]-4-phenyl-4H-1,2,4-triazole (CAS 339015-45-1)
- Ethyl 5-bromobenzo[d][1,3]dioxole-4-carboxylate (CAS 2092700-62-2)
- 3-Hydroxy-5,6-dioxo-2,3,5,6-tetrahydro-1H-indole-2-carboxylic acid (CAS 255884-97-0)
- 1,11-Dihydro-2H-pyrimido[4,5-a]carbazol-2-one (CAS 248246-47-1)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com