N-(5-Chloro-3-(phenylsulfonyl)-1H-indol-2-yl)nicotinamide CAS 918493-37-5
| CAS No. | 918493-37-5 |
| Molecular Formula | C20H14ClN3O3S |
| Molecular Weight | 411.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 411.86 g/mol gives N-(5-Chloro-3-(phenylsulfonyl)-1H-indol-2-yl)nicotinamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(5-Chloro-3-(phenylsulfonyl)-1H-indol-2-yl)nicotinamide (CAS 918493-37-5), molecular formula C20H14ClN3O3S and molecular weight 411.86 g/mol, is a CATO reference standard with documented purity and traceability.
N-(5-Chloro-3-(phenylsulfonyl)-1H-indol-2-yl)nicotinamide (C20H14ClN3O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-(5-Chloro-3-(phenylsulfonyl)-1H-indol-2-yl)nicotinamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H14ClN3O3S |
| Molecular Weight | 411.86 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- 1-(5-Chloro-2-nitrobenzenesulfonyl)-4-(2-methoxyphenyl)piperazine (CAS 866153-18-6)
- 4-Chloro-N-(4-(quinoxalin-2-yloxy)phenyl)benzenesulfonamide (CAS 400080-03-7)
- 4-Chloro-N-[(4E)-2-oxo-3-phenyl-1,2,3,4-tetrahydroquinazolin-4-ylidene]benzene-1-sulfonamide (CAS 478044-04-1)
- Ethyl 6-chloro-4-(4-methoxybenzenesulfonyl)-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate (CAS 866134-51-2)
- N-(5-Chloro-3-(phenylsulfonyl)-1H-indol-2-yl)isonicotinamide (CAS 918493-44-4)
- (2E)-1-{3-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-3-[(4-methoxyphenyl)amino]prop-2-en-1-one (CAS 478039-46-2)
- (2E)-1-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-3-[(4-methoxyphenyl)amino]prop-2-en-1-one (CAS 477871-15-1)
- (2E)-3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-N-(4-methoxyphenyl)prop-2-enamide (CAS 477870-77-2)
Recommended Standards
- N'-[(1E)-{3-chloro-4-[(4-fluorophenyl)methoxy]phenyl}methylidene]-2-(phenylamino)acetohydrazide (CAS 329777-98-2)
- N-(4-Chlorophenyl)-2-((5-(3-hydroxynaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide (CAS 332377-30-7)
- 5-(Chloromethyl)-4-(phenethoxymethyl)-2-(4-(trifluoromethyl)phenyl)thiazole (CAS 444613-00-7)
- N-(4-chlorophenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide (CAS 477872-25-6)
- N-Phenyl-2-(di-t-butylphosphino)pyrrole 672937-61-0 1-PHENYL-2-(DI-TERT-BUTYL-PHOSPHINO)-1H-PYRROLE;2-(DI-TERT-BUTYL-PHOSPHINO)-1-PHENYL-1H-PYRROLE;2-[BIS(1,1-DIMETHYLETHYL)PHOSPHINO]-1-PHENYL-1H-PYRROLE;CATACXIUM PTB;CATACXIUM(R) PTB;N-PHENYL-2-(DI-T-BUTYLPHOSPHINO)PYRROLE;N-PHENYL-2-(DI-TERT-BUTYLPHOSPHINO)PYRROLE;N-PHENYLPYRROL-2-YLDI-TERT-BUTYLPHOSPHINE SC11199 (CAS 672937-61-0)
- 6-(4-Chlorophenyl)-2-{[(2E)-3-phenylprop-2-en-1-yl]sulfanyl}-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 338751-64-7)
- (S)-1-(3-methoxy-4-methylphenyl)butan-1-amine (CAS 1259714-34-5)
- 1,1,1-Trifluoro-4-(methylsulfanyl)butan-2-amine (CAS 1554-62-7)
- 1,4-Bis[4-(di-p-tolylamino)styryl]benzene (CAS 55035-43-3)
- 4-Bromo-5-chlorothiophene-2-sulfonyl chloride (CAS 166964-35-8)
- 2-(4-Fluorophenyl)pyrrole (CAS 110319-94-3)
- 2-(Pentafluoro-l6-sulfanyl)acetic acid (CAS 89326-17-0)
- 4-(Ethylthio)tetrahydro-2h-pyran-4-carboxylic acid (CAS 1247341-86-1)
- Semaglutide Impurity 137 (x TFA Salt) (CAS CATO-C4X-2226137)
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