5-(Chloromethyl)-4-(phenethoxymethyl)-2-(4-(trifluoromethyl)phenyl)thiazole CAS 444613-00-7

Purity 97%+In StockPharmaceutical Standards
CAS No.444613-00-7
Molecular FormulaC20H17ClF3NOS
Molecular Weight411.87 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(Chloromethyl)-4-(phenethoxymethyl)-2-(4-(trifluoromethyl)phenyl)thiazole CAS 444613-00-7 chemical structure

Description

The molecular framework of 5-(Chloromethyl)-4-(phenethoxymethyl)-2-(4-(trifluoromethyl)phenyl)thiazole (C20H17ClF3NOS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

5-(Chloromethyl)-4-(phenethoxymethyl)-2-(4-(trifluoromethyl)phenyl)thiazole (CAS 444613-00-7) is a high-purity analytical reference standard with the molecular formula C20H17ClF3NOS and a molecular weight of 411.87 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(Chloromethyl)-4-(phenethoxymethyl)-2-(4-(trifluoromethyl)phenyl)thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H17ClF3NOS
Molecular Weight411.87 g/mol
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms1
Sulfur Atoms1

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