Ceftriaxone EP Impurity A CAS 92143-31-2
| CAS No. | 92143-31-2 |
| Molecular Formula | C18H18N8O7S3 |
| Molecular Weight | 554.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ceftriaxone EP Impurity A (C18H18N8O7S3) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Ceftriaxone EP Impurity A (CAS 92143-31-2), a pharmacopoeial impurity reference standard (molecular formula C18H18N8O7S3, MW 554.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ceftriaxone EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18N8O7S3 |
| Molecular Weight | 554.58 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 3 |
Related Ceftriaxone Standards
- Ceftriaxone Impurity 11 (CAS CATO-C4X-116311)
- Δ3-Ceftriaxone Isomer Impurity (CAS CATO-C4X-116314)
- Ceftriaxone Impurity 22 (CAS CATO-C4X-116322)
- Ceftriaxone Impurity 40 (CAS CATO-C4X-116340)
- Ceftriaxone Impurity 44 (CAS CATO-C4X-116344)
- Ceftriaxone impurity 53 (CAS CATO-C4X-116353)
- Ceftriaxone (CAS 73384-59-5)
- Ceftriaxone Impurity 27 (CAS CATO-C4X-116327)
Recommended Standards
- Ubrogepant D5 (CAS CATO-C4X-34025)
- Relugolix Impurity 116 (CAS 2814571-32-7)
- Ticagrelor Impurity 13 (CAS 274693-39-9)
- (6R,7S)-Ceftriaxone Impurity (CAS CATO-C4X-116316)
- Letermovir Impurity 62 (CAS CATO-C4X-291562)
- Sertraline Impurity 60 (CAS CATO-C4X-134460)
- Ribavirin Impurity 40 (CAS 39215-01-5)
- 1-Hexanol (CAS 111-27-3)
- 3-[Benzyl-(toluene-4-sulfonyl)-amino]-2-methyl-propionic acid (CAS 301320-51-4)
- Rutamarin (CAS 13164-05-1)
- 2-Deoxyguanosine 3,5-Dibutanoate (CAS 79971-08-7)
- Fmoc-norArg(Mtr)-OH (CAS 1313054-68-0)
- n-(2-Fluorophenyl)tetrahydrothiophen-3-amine (CAS 1019533-54-0)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com