Sertraline Impurity 60 CAS CATO-C4X-134460
| CAS No. | CATO-C4X-134460 |
| Molecular Formula | C21H26ClNO |
| Molecular Weight | 343.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sertraline Impurity 60 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Sertraline Impurity 60 (CAS CATO-C4X-134460, C21H26ClNO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Sertraline Impurity 60 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 343.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H26ClNO |
| Molecular Weight | 343.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Sertraline Standards
- Sertraline Impurity 61 (CAS CATO-C4X-134461)
- Sertraline Impurity 62 (CAS CATO-C4X-134462)
- Sertraline Impurity 63 (CAS CATO-C4X-134463)
- Sertraline impurity 44 (CAS CATO-C4X-134444)
- Sertraline Acetamide (CAS 1097616-52-8)
- Sertraline Impurity 55 (CAS 147250-57-5)
- Sertraline N-Oxide (CAS 209473-00-7)
- Sertraline RC 16 (CAS 674768-11-7)
Recommended Standards
- rac-Clemastine Fumarate EP Impurity B (CAS 61771-18-4)
- 5-(4-Butylphenyl)-6-chloro-N-cyclopentyl-2-methylpyrimidin-4-amine (CAS 917895-67-1)
- 4,5-Diiodo-1H-pyrrole-2-carbonitrile (CAS 51148-01-7)
- N-(4-Chlorobenzyl)-4-(2-cyclohexylethoxy)aniline (CAS 1040693-12-6)
- Mirogabalin Impurity 20 (CAS CATO-C4X-292420)
- Amoxicillin Impurity 89 (CAS CATO-C4X-114889)
- Tolvaptan Impurity 25 (CAS 2921676-63-1)
- 4,4'-Dimethylbiphenyl (CAS 613-33-2)
- 3H-spiro[2-benzofuran-1,1'-cyclohexan]-4'-one (CAS 204192-41-6)
- 3-Cyclopropylisoxazol-5-amine (CAS 21080-91-1)
- 3-Methoxybenzyl 3-(piperidin-4-yloxy)benzo[b]thiophene-2-carboxylate (CAS 1416051-69-8)
- N-(1-acetylindolin-5-yl)acrylamide (CAS 1156699-07-8)
- 1-(1h-1,3-Benzodiazol-2-ylmethyl)piperidin-4-amine trihydrochloride (CAS 1334149-66-4)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com