2-((5-(Hydroxymethyl)-1-(2-(methylamino)-2-oxoethyl)-1H-imidazol-2-yl)thio)-N-(m-tolyl)acetamide CAS 923195-18-0
| CAS No. | 923195-18-0 |
| Molecular Formula | C16H20N4O3S |
| Molecular Weight | 348.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-((5-(Hydroxymethyl)-1-(2-(methylamino)-2-oxoethyl)-1H-imidazol-2-yl)thio)-N-(m-tolyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-((5-(Hydroxymethyl)-1-(2-(methylamino)-2-oxoethyl)-1H-imidazol-2-yl)thio)-N-(m-tolyl)acetamide (CAS 923195-18-0), molecular formula C16H20N4O3S and molecular weight 348.42 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-((5-(Hydroxymethyl)-1-(2-(methylamino)-2-oxoethyl)-1H-imidazol-2-yl)thio)-N-(m-tolyl)acetamide (C16H20N4O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H20N4O3S |
| Molecular Weight | 348.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Hydroxymethyl Standards
- Methyl 4-(((5-(hydroxymethyl)-1-(2-(methylamino)-2-oxoethyl)-1H-imidazol-2-yl)thio)methyl)benzoate (CAS 923677-52-5)
- N-(2-(hydroxymethyl)-2,3-dihydro-1H-benzo[f]chromen-1-yl)-N-methylbenzamide (CAS 317820-31-8)
- 2-Hydroxymethyl-17α-methylandrostadiene-11α,17β-diol-3-one (CAS 59400-02-1)
- [4-(Hydroxymethyl)-1-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]-1H-1,2,3-triazol-5-yl]methanol (CAS 861210-55-1)
- 4-((4-((4-(Hydroxymethyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile (CAS 823786-21-6)
- (2-(Hydroxymethyl)piperidin-1-yl)(4-iodophenyl)methanone (CAS 1156334-52-9)
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- 2-[3-(Hydroxymethyl)piperidino]-5-[(E)-1-naphthylmethylidene]-1,3-thiazol-4(5H)-one (CAS 866149-74-8)
Recommended Standards
- 2-((4-Methoxy-N-phenylphenyl)sulfonamido)-N,N-dimethylacetamide (CAS 339013-34-2)
- 2-(5-(Thiophen-2-yl)-1,10b-dihydro-5H-benzo[e]pyrazolo[1,5-c][1,3]oxazin-2-yl)phenol (CAS 896618-79-4)
- 2-((1-(2-Amino-2-oxoethyl)-5-(hydroxymethyl)-1H-imidazol-2-yl)thio)-N-(4-methylbenzyl)acetamide (CAS 921846-19-7)
- 2-(5-Methoxy-4-oxo-2-((pyrimidin-2-ylthio)methyl)pyridin-1(4H)-yl)-N-propylacetamide (CAS 920408-63-5)
- 1-(2-Methoxy-5-methylphenyl)ethane-1-thiol (CAS 1039963-77-3)
- 2-(((2-Bromocyclopentyl)oxy)methyl)tetrahydrofuran (CAS 1251142-60-5)
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