4-(2-Chloroacetyl)-N-methyl-3,4-dihydro-2h-benzo[b][1,4]oxazine-2-carboxamide CAS 923253-62-7
| CAS No. | 923253-62-7 |
| Molecular Formula | C12H13ClN2O3 |
| Molecular Weight | 268.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(2-Chloroacetyl)-N-methyl-3,4-dihydro-2h-benzo[b][1,4]oxazine-2-carboxamide.
4-(2-Chloroacetyl)-N-methyl-3,4-dihydro-2h-benzo[b][1,4]oxazine-2-carboxamide (CAS 923253-62-7) is a high-purity analytical reference standard with the molecular formula C12H13ClN2O3 and a molecular weight of 268.70 g/mol.
Structurally, 4-(2-Chloroacetyl)-N-methyl-3,4-dihydro-2h-benzo[b][1,4]oxazine-2-carboxamide (C12H13ClN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 268.70 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(2-Chloroacetyl)-N-methyl-3,4-dihydro-2h-benzo[b][1,4]oxazine-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13ClN2O3 |
| Molecular Weight | 268.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloroacetyl Standards
- 5-[4-(2-chloroacetyl)piperazin-1-yl]-2-methyl-1,3-oxazole-4-carbonitrile (CAS 1050910-17-2)
- N-[4-(2-chloroacetyl)phenyl]hexanamide (CAS 571150-64-6)
- n-{4-[4-(2-chloroacetyl)phenyl]butan-2-yl}acetamide (CAS 852840-56-3)
- methyl 4-(2-chloroacetyl)-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate (CAS 949980-36-3)
- Methyl 2-(2-chloroacetyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate (CAS 1008996-86-8)
- 6-(2-Chloroacetyl)-4-propyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 927965-53-5)
- Butyl 4-[(chloroacetyl)amino]benzoate (CAS 106214-24-8)
- 2-(Chloroacetyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline (CAS 111631-72-2)
Recommended Standards
- 4-(2-(4-Chlorophenoxy)acetyl)piperazin-2-one (CAS 923177-66-6)
- 4-Chloro-N-cyclopentyl-3-nitrobenzamide (CAS 339059-83-5)
- 2-Chloro-N-cyclopentyl-4-nitrobenzamide (CAS 300829-22-5)
- 5-((4-Chloro-3,5-dimethyl-1h-pyrazol-1-yl)methyl)furan-2-carbohydrazide (CAS 386705-59-5)
- 4-(Aminomethyl)-2-(difluoromethyl)-5-methylpyridin-3-ol (CAS 1806973-99-8)
- 2-Amino-4-methoxy-1-methylbenzimidazole (CAS 33235-33-5)
- 3-(3-Amino-1h-1,2,4-triazol-1-yl)-N-ethylpropanamide (CAS 1250024-20-4)
- 5-Methyl-N-(naphthalen-1-yl)isoxazole-4-carboxamide (CAS 61643-35-4)
- 6-(Trifluoromethyl)-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one (CAS 1393546-02-5)
- Beraprost Impurity 4(discontinue,see C4X-218413) (CAS CATO-C4X-21844)
- 3-Cyclopropyl-2-(4-methoxyphenyl)-3-oxopropanenitrile (CAS 95664-79-2)
- 2-Methyl-6-(trifluoromethyl)benzoic Acid (CAS 1104383-68-7)
- Posaconazole Impurity 23(S,R,S,R) (CAS 213381-04-5)
- Fibrinogen-Binding Inhibitor Peptide (CAS 89105-94-2)
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