7-Chloro-2-methyl-2H-pyrazolo[4,3-d]pyrimidine CAS 923282-41-1
| CAS No. | 923282-41-1 |
| Molecular Formula | C6H5ClN4 |
| Molecular Weight | 168.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Chloro-2-methyl-2H-pyrazolo[4,3-d]pyrimidine.
CATO supplies 7-Chloro-2-methyl-2H-pyrazolo[4,3-d]pyrimidine (CAS 923282-41-1), a certified reference material (molecular formula C6H5ClN4, MW 168.58 g/mol) for analytical method development and quality control.
The molecular framework of 7-Chloro-2-methyl-2H-pyrazolo[4,3-d]pyrimidine (C6H5ClN4) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5ClN4 |
| Molecular Weight | 168.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-1H-pyrrolo[3,2-c]pyridin-2(3H)-one (CAS 1000342-80-2)
- 4-Chloro-2-methoxypyridine-3-carbonitrile (CAS 1008451-56-6)
- 6-Chloro-2-methyl-9H-purine (CAS 100859-35-6)
- 3-chloro-6-methyl-[1,2,4]triazolo[4,3-a]pyrimidine (CAS 1019033-24-9)
- 2-Chloro-8-methyl-9H-purine (CAS 1023813-16-2)
- 2-Chloro-5-methylfuro[2,3-d]pyrimidine (CAS 1030377-49-1)
- 7-chloro-5-methyl-1H-pyrazolo[4,3-d]pyrimidine (CAS 1055057-37-8)
- 2-Chloro-6-hydrazinylpyridine-4-carbonitrile (CAS 107445-56-7)
Recommended Standards
- 7-Chloro-1-methylpyrazolo[4,3-d]pyrimidine (CAS 923282-39-7)
- 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 24415-66-5)
- 7-Chloro-1H-pyrazolo[3,4-c]pyridin-3-amine (CAS 2168024-03-9)
- 7-chlorobenzo[d]isoxazol-3-amine (CAS 927413-64-7)
- 6-Chloro-2-(3-(trifluoromethyl)phenyl)tetrahydro-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione (CAS 318959-11-4)
- (4-((4-Methyl-1,4-diazepan-1-yl)methyl)phenyl)methanol (CAS 884507-50-0)
- tert-Butyl 4-(5-(1-aminopropyl)pyridin-2-yl)piperazine-1-carboxylate (CAS 1355230-76-0)
- 4-Undecanoyl-1H-pyrrole-2-carboxamide (CAS 251096-63-6)
- 3-(5-(Tetrahydro-2h-pyran-4-yl)-4h-1,2,4-triazol-3-yl)propan-1-amine (CAS 1481660-99-4)
- 4-((9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)amino)naphthalene-1,2-dione (CAS 671782-38-0)
- Bicyclo[2.2.2]-octane-2-carboxamide (CAS 18784-45-7)
- 2-(2,2-difluoro-2H-1,3-benzodioxol-4-yl)ethan-1-ol (CAS 334778-39-1)
- 2,6-Di-tert-butyl-4-ethynylphenol (CAS 36384-85-7)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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