6-Chloro-2-(3-(trifluoromethyl)phenyl)tetrahydro-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione CAS 318959-11-4
| CAS No. | 318959-11-4 |
| Molecular Formula | C13H10ClF3N2O2 |
| Molecular Weight | 318.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 6-Chloro-2-(3-(trifluoromethyl)phenyl)tetrahydro-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione (CAS 318959-11-4), a certified reference material (molecular formula C13H10ClF3N2O2, MW 318.68 g/mol) for analytical method development and quality control.
6-Chloro-2-(3-(trifluoromethyl)phenyl)tetrahydro-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione (C13H10ClF3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-2-(3-(trifluoromethyl)phenyl)tetrahydro-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10ClF3N2O2 |
| Molecular Weight | 318.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-(2-Chloro-phenyl)-5-trifluoromethyl-2H-pyrazole-3-carboxylic acid ethyl ester (CAS 1033586-26-3)
- 1-{1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-methyl-1H-imidazol-4-yl}-1-ethanone oxime (CAS 251096-48-7)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(furan-2-ylmethyl)acetamide (CAS 691870-10-7)
- 5-Chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one (CAS 2381044-50-2)
- 6-Chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one (CAS 2869830-81-7)
- Ethyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrole-2-carboxylate (CAS 321430-87-9)
- N-(3-Chloro-2-fluorophenyl)-6-nitroquinazolin-4-amine (CAS 1290545-22-0)
- N-(3-Chloro-4-fluorophenyl)-6-nitroquinazolin-4-amine (CAS 184356-50-1)
Recommended Standards
- Ethyl 5-(4-chlorophenyl)-2-(trifluoromethyl)furan-3-carboxylate (CAS 175276-59-2)
- Ethyl 4-(4-chlorophenyl)-2-(trifluoromethyl)-1h-imidazole-5-carboxylate (CAS 162700-26-7)
- (2R,3R,4S,5R)-5-(2-Chloro-6-methoxy-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 758705-70-3)
- Ethyl 1-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 112055-36-4)
- Methyl 4-bromo-5-(3-bromophenyl)-1h-pyrazole-3-carboxylate (CAS 1239484-03-7)
- 3-([1,1'-Biphenyl]-4-yl)propan-1-amine (CAS 872215-02-6)
- 2-(4-Heptyloxybenzoyl)oxazole (CAS 898760-32-2)
- Solriamfetol Impurity 25 (CAS CATO-C4X-256325)
- Isooctadecenylsuccinic Anhydride(mixture of branched chain isomers) (CAS 58239-72-8)
- tert-Butyl (5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)carbamate (CAS 1346447-44-6)
- (S)-N1-Cyclopropyl-N1-(1-methylpiperidin-3-yl)ethane-1,2-diamine (CAS 1354014-96-2)
- {[(1R,2R)-2-Amino-1,2-diphenylethyl](4-toluenesulfonyl)amido}(p-cymene)(pyridine)ruthenium(II) (CAS 1192483-14-9)
- 5-Acetyl-2-((4-ethoxyphenyl)amino)-4-methylthiazol-3-ium chloride (CAS 469890-02-6)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com