2-Chloro-1-[4-(3-chloro-4-fluorobenzenesulfonyl)piperazin-1-yl]ethan-1-one CAS 923780-46-5
| CAS No. | 923780-46-5 |
| Molecular Formula | C12H13Cl2FN2O3S |
| Molecular Weight | 355.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-1-[4-(3-chloro-4-fluorobenzenesulfonyl)piperazin-1-yl]ethan-1-one.
2-Chloro-1-[4-(3-chloro-4-fluorobenzenesulfonyl)piperazin-1-yl]ethan-1-one (CAS 923780-46-5) is a high-purity analytical reference standard with the molecular formula C12H13Cl2FN2O3S and a molecular weight of 355.21 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-Chloro-1-[4-(3-chloro-4-fluorobenzenesulfonyl)piperazin-1-yl]ethan-1-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 355.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-1-[4-(3-chloro-4-fluorobenzenesulfonyl)piperazin-1-yl]ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13Cl2FN2O3S |
| Molecular Weight | 355.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- Methyl 2-(2-chloro-6-fluorophenyl)-4-(4-chlorophenyl)-4-oxobutanoate (CAS 344281-42-1)
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- 4-Chloro-2-{[(4-chlorophenyl)sulfanyl]methyl}-5,6-dimethylthieno[2,3-d]pyrimidine (CAS 793727-83-0)
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Recommended Standards
- 2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide Benzenesulfonic Acid (CAS 326886-05-9)
- 3-(Benzylamino)-2-iodo-5,5-dimethylcyclohex-2-en-1-one (CAS 51924-73-3)
- 2-((4-Bromophenyl)sulfonamido)benzamide (CAS 333441-46-6)
- 4-((4-(4-Bromophenyl)thiazol-2-yl)amino)-4-oxobutanoic acid (CAS 71591-70-3)
- N,N-Dibenzyl-3-bromopropan-1-amine (CAS 98346-35-1)
- 7-Methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-2-carboxylic acid methyl ester (CAS 2407051-35-6)
- 8-Ethoxy-3,4-dihydro-2h-1-benzopyran-3-carboxylic acid (CAS 923243-36-1)
- 3-Ethyl-6,7-dimethoxyquinazoline-2,4(1H,3H)-dione (CAS 335417-99-7)
- 1-Ethylpiperidine-4-carbonitrile (CAS 88654-16-4)
- N,N-Diethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide (CAS 911228-95-0)
- Eliglustat Impurity 7 (CAS 491833-30-8)
- 1-(Benzenesulfonyl)butan-2-amine (CAS 1017140-16-7)
- Methyl 6-formyl-2-naphthoate (CAS 7567-87-5)
- Des-[Gly]31-Semaglutide(x TFA Salt) (CAS 873874-39-6(free base))
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