2-((1H-Indol-3-yl)methyl)-6-fluoro-3-hydroxyquinoline-4-carboxylic acid CAS 924634-83-3
| CAS No. | 924634-83-3 |
| Molecular Formula | C19H13FN2O3 |
| Molecular Weight | 336.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((1H-Indol-3-yl)methyl)-6-fluoro-3-hydroxyquinoline-4-carboxylic acid is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-((1H-Indol-3-yl)methyl)-6-fluoro-3-hydroxyquinoline-4-carboxylic acid (CAS 924634-83-3) is a high-purity analytical reference standard with the molecular formula C19H13FN2O3 and a molecular weight of 336.32 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-((1H-Indol-3-yl)methyl)-6-fluoro-3-hydroxyquinoline-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 336.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((1H-Indol-3-yl)methyl)-6-fluoro-3-hydroxyquinoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H13FN2O3 |
| Molecular Weight | 336.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related H Standards
- 2-((1H-Indol-3-yl)methyl)-8-fluoro-3-hydroxyquinoline-4-carboxylic acid (CAS 924634-66-2)
- 5-(Indol-3-ylmethyl)-4-(4-methoxyphenyl)-1,2,4-triazole-3-thiol (CAS 1024523-01-0)
- 1-(2-(1H-indol-3-yl)ethyl)-3-(2,6-diethylphenyl)urea (CAS 1024385-32-7)
- 2-(1H-Indol-3-yl)-4-oxo-4-[4-(propan-2-yl)phenyl]butanoic acid (CAS 937605-12-4)
- 1-(1H-indol-3-yl)-2-(4-(pyrimidin-2-yl)piperazin-1-yl)ethane-1,2-dione (CAS 497060-86-3)
- 4-(((1H-Indol-3-yl)methylene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 676151-26-1)
- 2-[2-(1h-indol-3-yl)ethyl]-1,3-dioxo-2,3-dihydro-1h-isoindole-5-carboxylic acid (CAS 296266-01-8)
- 4-(4-(1h-Indol-4-yl)-3,4,6,7-tetrahydro-5h-imidazo[4,5-c]pyridin-5-yl)-4-oxobutanoic acid (CAS 1071914-00-5)
Recommended Standards
- 1-Methyl-5-(4-(pyridin-2-yl)piperazin-1-yl)-3-(trifluoromethyl)-1H-pyrazole-4-carbonitrile (CAS 324009-11-2)
- 1-Methyl-4-(5-methyl-4-(3-(trifluoromethyl)benzyl)-4H-1,2,4-triazol-3-yl)-1H-pyrazol-5-amine (CAS 955976-92-8)
- 2-(2-Methyl-5-nitrobenzenesulfonamido)benzoic acid (CAS 93805-04-0)
- 1-(Methylsulfonyl)-2-nitrobenzene (CAS 2976-34-3)
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- (S)-3-Amino-2-methyl-5-(methylthio)pentan-2-ol (CAS 168648-49-5)
- Bis(2-methylallyl)amine hydrochloride (CAS 44844-90-8)
- Obeticholic Acid Impurity 13 (CAS 1537866-49-1)
- H-m-Fluoro-D-Phe-OMe · HCl (CAS 201479-09-6)
- 14H-spiro[dibenzo[c,h]acridine-7,9'-fluorene] (CAS 1303969-19-8)
- H-Leu-NH2 (CAS 687-51-4)
- Edoxaban Impurity 105 (CAS 2803477-33-8)
- N-(4-Amino-2-methylphenyl)butanamide hydrochloride (CAS 1184988-39-3)
- Peptide Impurity 27 (CAS 1350456-68-6)
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