Edoxaban Impurity 105 CAS 2803477-33-8
| CAS No. | 2803477-33-8 |
| Molecular Formula | C9H9ClN2O3 |
| Molecular Weight | 228.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Edoxaban Impurity 105 (CAS 2803477-33-8), a pharmacopoeial impurity reference standard (molecular formula C9H9ClN2O3, MW 228.63 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C9H9ClN2O3, Edoxaban Impurity 105 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 228.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Edoxaban Impurity 105 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9ClN2O3 |
| Molecular Weight | 228.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Edoxaban Standards
- Edoxaban Impurity 34 (CAS 1700085-03-5)
- Edoxaban Impurity 77 (CAS CATO-C4X-106377)
- Edoxaban Impurity 93 (CAS 349125-08-2)
- Edoxaban Impurity 48 (CAS 143150-92-9)
- Edoxaban Impurity 98 (CAS 365997-32-6)
- Edoxaban Impurity 107 (CAS CATO-C4X-1063107)
- Edoxaban Impurity 113 (CAS CATO-C4X-1063113)
- Edoxaban impurity 133 (CAS CATO-C4X-1063133)
Recommended Standards
- N-(5-Chloro-4-methyl-2-nitrophenyl)acetamide (CAS 7149-78-2)
- N-(5-chloro-2-methyl-3-nitrophenyl)acetamide (CAS 885519-52-8)
- N-(4-chloro-3-nitrophenyl)propionamide (CAS 5540-61-4)
- N-(4-chloro-2-nitrophenyl)propionamide (CAS 86569-51-9)
- Dapagliflozin Impurity 207 (CAS CATO-C4X-1138207)
- Edaravone impurity 47 (CAS 53341-66-5)
- Nintedanib Impurity 10 (CAS 2037385-84-3)
- (1S)-1-cyclopropyl-2,2,2-trifluoroethan-1-amine hydrochloride (CAS 1338377-73-3)
- 2-(4-Ethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione (CAS 130872-49-0)
- 1-Cyclohexyl-6,7-difluoro-1,2,3-benzotriazole (CAS 1365271-73-3)
- Methyl quinuclidine-2-carboxylate (CAS 30740-19-3)
- 1-(2-Ethylphenyl)-1H-pyrrole-3-carbaldehyde (CAS 881040-90-0)
- 4-(8-Bromo-2-chloroquinazolin-4-yl)morpholine (CAS 1374208-47-5)
- Tirzepatide Impurity 26 X TFA Salt (CAS CATO-C4X-324026)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com