4-(2-Amino-4-chlorophenyl)-2-piperazinone CAS 926239-48-7
| CAS No. | 926239-48-7 |
| Molecular Formula | C10H12ClN3O |
| Molecular Weight | 225.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(2-Amino-4-chlorophenyl)-2-piperazinone.
4-(2-Amino-4-chlorophenyl)-2-piperazinone (CAS 926239-48-7), molecular formula C10H12ClN3O and molecular weight 225.67 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(2-Amino-4-chlorophenyl)-2-piperazinone (C10H12ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(2-Amino-4-chlorophenyl)-2-piperazinone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12ClN3O |
| Molecular Weight | 225.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-7-chloro-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid (CAS 1196152-15-4)
- Methyl 1-amino-6-chloro-2,3-dihydro-1H-indene-4-carboxylate (CAS 1391063-99-2)
- Methyl 3-amino-7-chloro-2,3-dihydro-1H-indene-5-carboxylate (CAS 1391319-31-5)
- Methyl 2-amino-5-chloro-2,3-dihydro-1H-indene-2-carboxylate (CAS 1550026-34-0)
- 2-Amino-6-chloro-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid (CAS 74444-73-8)
- 4-(2-Amino-6-chlorophenyl)-2-piperazinone (CAS 926260-60-8)
- 4-(4-Amino-2-chlorophenyl)piperazin-2-one (CAS 926250-84-2)
- Ethyl 3-(2-amino-4-chlorophenyl)acrylate (CAS 397328-49-3)
Recommended Standards
- 3-Chloro-n-(phenylacetyl)propanamide (CAS 4488-98-6)
- 3-chloro-N-(2-oxo-2-phenylethyl)propanamide (CAS 70680-55-6)
- 4-(3-Chlorobenzoyl)morpholine (CAS 26162-86-7)
- 3-Chloro-5-methoxy-4-propoxybenzonitrile (CAS 693804-16-9)
- N-(2-Morpholinoethyl)undec-10-enamide (CAS 102613-07-0)
- Ethyl 5-chloro-1-phenyl-1H-pyrazole-3-carboxylate (CAS 85174-68-1)
- 7-(Phenyl(quinolin-3-ylamino)methyl)quinolin-8-ol (CAS 73855-37-5)
- (2-(4-(Benzyloxy)phenyl)thiazol-4-yl)methanamine (CAS 885280-65-9)
- Methyl (2S,3S)-2,3-dihydroxybutanoate (CAS 1932552-43-6)
- (2S,4R)-1-Boc-4-hydroxy-2-methylpyrrolidine (CAS 114676-61-8)
- 7-(Chlorodifluoromethyl)-2-(4-phenylpiperazin-1-yl)-5-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 439096-13-6)
- 4-chloro-2-[(phenylthio)methyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine (CAS 128277-14-5)
- IRGANOX 3052 (CAS 61167-58-6)
- Endo-Gly4-Semaglutide (CAS CATO-C4X-222679)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com