2-Amino-6-chloro-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid CAS 74444-73-8
| CAS No. | 74444-73-8 |
| Molecular Formula | C11H12ClNO2 |
| Molecular Weight | 225.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-Amino-6-chloro-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid (C11H12ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 225.67 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Amino-6-chloro-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid (CAS 74444-73-8) is a high-purity analytical reference standard with the molecular formula C11H12ClNO2 and a molecular weight of 225.67 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12ClNO2 |
| Molecular Weight | 225.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- 2-Amino-7-chloro-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid (CAS 1196152-15-4)
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Recommended Standards
- 2-(7-Chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)propan-2-ol (CAS 2387596-80-5)
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- 2-(7-Chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)propan-1-ol (CAS 2387601-60-5)
- 2-Chloro-1-(6-methoxyindolin-1-yl)ethanone (CAS 793672-17-0)
- 3,6-dimethyl-[1,2]oxazolo[5,4-b]pyridine-4-carbohydrazide (CAS 938022-08-3)
- Ethyl 2-(trifluoroacetyl)-3-(N,N-dimethylamino)-2-propenoate (CAS 267243-86-7)
- 1-(3-Methylbenzyl)-1h-indol-3-yl carbamimidothioate hydroiodide (CAS 1049785-01-4)
- Limaprost Impurity 9 (CAS CATO-C4X-21459)
- N-cyano-N-methyl-3-(methylsulfanyl)aniline (CAS 222734-73-8)
- Eltrombopag Impurity 88 (CAS CATO-C4X-119888)
- 2-(4-Chlorobenzoyl)-3-{[3-(trifluoromethyl)benzenesulfonyl]methyl}-1-benzofuran (CAS 338411-53-3)
- (E)-Cefuroxime Sodium Impurity 43 (CAS CATO-C4X-124543)
- 2H-Selenopheno[3,2-g]thiochromen-2-one (CAS 143810-62-2)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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