5-Amino-2-chloro-N-(pyridin-2-yl)benzamide CAS 926273-21-4
| CAS No. | 926273-21-4 |
| Molecular Formula | C12H10ClN3O |
| Molecular Weight | 247.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Amino-2-chloro-N-(pyridin-2-yl)benzamide (CAS 926273-21-4) is a high-purity analytical reference standard with the molecular formula C12H10ClN3O and a molecular weight of 247.68 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 5-Amino-2-chloro-N-(pyridin-2-yl)benzamide is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 247.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 5-Amino-2-chloro-N-(pyridin-2-yl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10ClN3O |
| Molecular Weight | 247.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 3-Amino-N-(5-chloropyridin-2-yl)benzamide (CAS 1039827-87-6)
- N-(5-amino-2-chlorophenyl)isonicotinamide (CAS 1082186-72-8)
- 4-Amino-2-chloro-N-(pyridin-3-yl)benzamide (CAS 19084-14-1)
- (2-Amino-5-chlorophenyl)(2-hydroxyphenyl)methanone (CAS 62492-57-3)
- (2-Amino-5-chlorophenyl)(3-hydroxyphenyl)methanone (CAS 62492-58-4)
- 2-Amino-4-chloro-N-(pyridin-3-yl)benzamide (CAS 926224-60-4)
- 2-Amino-5-chloro-4-hydroxybenzophenone (CAS 784-41-8)
- 2-amino-5-chloro-N-(pyridin-4-yl)benzamide (CAS 926194-69-6)
Recommended Standards
- 5-(Benzyloxy)-6-chloropicolinaldehyde (CAS 59781-07-6)
- 5-Amino-2-chloro-N-(pyridin-3-yl)benzamide (CAS 896160-34-2)
- 5-(4-Chlorophenoxy)-1,3-dimethyl-1H-pyrazole-4-carbonitrile (CAS 956372-08-0)
- 5-Chloro-2-(pyridin-3-ylmethoxy)benzaldehyde (CAS 926257-17-2)
- 3-((1,2,3,4-Thiatriazol-5-yl)amino)benzenesulfonamide (CAS 91772-19-9)
- 6-Fluoro-3,4-dihydroisoquinolin-1(2H)-one (CAS 214045-84-8)
- Methyl 5-amino-1,3,4-thiadiazole-2-carboxylate (CAS 227958-69-2)
- n-[4-bromo-3-(trifluoromethyl)phenyl]-2-chloroacetamide (CAS 40992-67-4)
- Dimethyl 5-(m-tolyl)-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate 2-oxide (CAS 339113-52-9)
- n-Hydroxy-2'-oxo-3,4-dihydro-1h-spiro[naphthalene-2,3'-piperidine]-6-carboxamide (CAS 2028327-60-6)
- Sordarin Sodium Salt (CAS 463356-00-5)
- 2-Bromo-3-fluorotoluene (CAS 59907-13-0)
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- Semaglutide impurity 49 (CAS CATO-C4X-222649)
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