Trimetazidine Impurity 13 CAS 92700-82-8
| CAS No. | 92700-82-8 |
| Molecular Formula | C15H22N2O4 |
| Molecular Weight | 294.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Trimetazidine Impurity 13 (CAS 92700-82-8, C15H22N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Trimetazidine Impurity 13 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 294.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H22N2O4 |
| Molecular Weight | 294.35 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Nitrogen Atoms | 2 |
Related Trimetazidine Standards
- Trimetazidine Impurity 24 (CAS 92432-50-3)
- Trimetazidine Impurity 28 (CAS CATO-C4X-180328)
- Trimetazidine Impurity 29 (CAS CATO-C4X-180329)
- Trimetazidine Impurity 30 (CAS CATO-C4X-180330)
- Trimetazidine Impurity 18 (CAS CATO-C4X-180318)
- Trimetazidine Impurity 2 (CAS 93152-26-2)
- Trimetazidine-d8 Dihydrochloride (CAS 1219908-67-4)
- Trimetazidine (CAS 5011-34-7)
Recommended Standards
- Atenolol Impurity 26 (CAS CATO-C4X-154926)
- Lacosamide Impurity 60 (CAS CATO-C4X-183060)
- Zolpidem Impurity 10 (CAS 258273-50-6)
- Tolvaptan Impurity 60 (CAS CATO-C4X-195560)
- Rivaroxaban Impurity 7(S-isomer) (CAS 161596-47-0)
- Semaglutide impurity 99 (CAS CATO-C4X-222699)
- Tofacitinib Impurity 82 (CAS CATO-C4X-107982)
- N1-Methyl-4-nitro-1,2-benzenediamine (CAS 41939-61-1)
- 5-(Benzyloxy)-2-ethyl-4-methylpyrimidine (CAS 1369766-63-1)
- PPT (CAS 1019842-99-9)
- 2-{1-benzyl-3-methyl-2,4,6-trioxo-1H,2H,3H,4H,5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}acetic acid (CAS 726152-43-8)
- 2-(4-Methoxybenzoyl)furan (CAS 15970-74-8)
- Methyl 1-(2-fluorophenyl)-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011398-46-1)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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