N-tert-Butyl-2-chlorobenzene-1-sulfonamide CAS 92811-11-5
| CAS No. | 92811-11-5 |
| Molecular Formula | C10H14ClNO2S |
| Molecular Weight | 247.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N-tert-Butyl-2-chlorobenzene-1-sulfonamide (CAS 92811-11-5), molecular formula C10H14ClNO2S and molecular weight 247.74 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-tert-Butyl-2-chlorobenzene-1-sulfonamide (C10H14ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14ClNO2S |
| Molecular Weight | 247.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Recommended Standards
- N-Butyl-4-chlorobenzenesulfonamide (CAS 6419-73-4)
- Urapidil Impurity 88 (CAS 13379-99-2)
- N-benzyl-3-chloropropane-1-sulfonamide (CAS 90945-14-5)
- Diethyltin Dichloride (CAS 866-55-7)
- 4-Carboxy-2,6-bis(4-methoxy-3-sulfophenyl)pyridin-1-ium perchlorate (CAS 91788-39-5)
- O2-tert-Butyl O3-methyl (3S)-7-fluoro-2-azabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate (CAS 1957130-60-7)
- 4,8-Dimethyldecanal (CAS 75983-36-7)
- (5-Methyl-1,3-thiazol-2-yl)acetonitrile (CAS 851269-14-2)
- 1-(2,2-difluoroethyl)-N-(4-methoxybenzyl)-1H-pyrazol-4-amine (CAS 1170978-83-2)
- 2-Methoxy-3-(3-methyl-2-thenoyl)pyridine (CAS 898785-87-0)
- 2-(2-Fluorobenzoyl)pyridine (CAS 6238-65-9)
- N,N-Dibenzylethanamine (CAS 10479-25-1)
- 4-Fluoro-2-[(1E)-(hydroxyimino)methyl]phenol (CAS 2059178-06-0)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com