Urapidil Impurity 88 CAS 13379-99-2

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.13379-99-2
Molecular FormulaC10H14ClNO2S
Molecular Weight247.74 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Urapidil Impurity 88 CAS 13379-99-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 247.74 g/mol gives Urapidil Impurity 88 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Urapidil Impurity 88 (CAS 13379-99-2) is a certified pharmaceutical impurity reference standard with the molecular formula C10H14ClNO2S and a molecular weight of 247.74 g/mol.

Urapidil Impurity 88 (C10H14ClNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H14ClNO2S
Molecular Weight247.74 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1960
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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