Vonoprazan Fumarate Impurity 111 CAS 928325-69-3
| CAS No. | 928325-69-3 |
| Molecular Formula | C17H15ClFN3O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Vonoprazan Fumarate Impurity 111 is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Vonoprazan Fumarate Impurity 111 (CAS 928325-69-3, C17H15ClFN3O2SC4H4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Vonoprazan Fumarate Impurity 111 (C17H15ClFN3O2SC4H4O4) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 495.91 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Vonoprazan Fumarate Impurity 111 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H15ClFN3O2S C4H4O4 |
| Molecular Weight | 495.91 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Vonoprazan Standards
- Vonoprazan Impurity 298 (CAS 103860-56-6)
- Vonoprazan Impurity 82 (CAS 106058-86-0)
- Vonoprazan Fumarate Impurity 71 (CAS 1060802-18-7)
- Vonoprazan Impurity 129 (CAS 109-00-2)
- Vonoprazan Impurity 188 (CAS 111480-82-1)
- Vonoprazan Impurity 195 (CAS 1126403-28-8)
- Vonoprazan Impurity 10 (CAS 122453-85-4)
- Vonoprazan Impurity 89 (CAS 1224739-02-9)
Recommended Standards
- Fluralaner Impurity 48 (CAS CATO-C4X-218048)
- Darolutamide impurity 9 (CAS CATO-C4X-31069)
- Salbutamol Impurity 176 (CAS CATO-C4X-1176176)
- 4-Amino-2-chloro-n-methylbenzamide (CAS 926203-17-0)
- 2-Cyclobutylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1517974-95-6)
- Gefitinib Impurity 42 (CAS 230955-75-6)
- 4-(3-(2-(2-Chloro-4-nitrophenoxy)ethyl)ureido)benzene-1-sulfonyl fluoride (CAS 25240-47-5)
- 4-Bromo-2-chlorophenyl acetate (CAS 102932-05-8)
- (5-(Benzo[d][1,3]dioxol-5-yl)-1,2,4-oxadiazol-3-yl)methanamine hydrochloride (CAS 1185302-68-4)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788692)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com