4-Chloro-3-(difluoromethoxy)benzenesulfonyl chloride CAS 929341-75-3
| CAS No. | 929341-75-3 |
| Molecular Formula | C7H4Cl2F2O3S |
| Molecular Weight | 277.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Chloro-3-(difluoromethoxy)benzenesulfonyl chloride (CAS 929341-75-3) is a high-purity analytical reference standard with the molecular formula C7H4Cl2F2O3S and a molecular weight of 277.07 g/mol.
The molecular framework of 4-Chloro-3-(difluoromethoxy)benzenesulfonyl chloride (C7H4Cl2F2O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-Chloro-3-(difluoromethoxy)benzenesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4Cl2F2O3S |
| Molecular Weight | 277.07 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-4-(difluoromethoxy)benzenesulfonyl chloride (CAS 1016714-35-4)
- 5-Chloro-2-(difluoromethoxy)benzene-1-sulfonyl chloride (CAS 1082821-83-7)
- 4-Chloro-N-(4-chloro-2-nitrophenyl)butanamide (CAS 1284661-62-6)
- 4-Chloro-N-(2-chloro-5-nitrophenyl)butanamide (CAS 540755-52-0)
- 5-Chloro-n'-(2-chloroacetyl)-2-methoxybenzohydrazide (CAS 743444-48-6)
- 5-Chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxylic acid (CAS 1047630-61-4)
- 2-Chloro-1-(4-chlorobenzyl)-1H-benzo[d]imidazole, 95% (CAS 131705-80-1)
- 2-(Chloro(4-chlorophenyl)methyl)benzofuran (CAS 82158-53-0)
Recommended Standards
- 2-Bromonaphthalene-1,8-dicarboxylic Anhydride (CAS 21563-29-1)
- 5-Bromobenzo[de]isochromene-1,3-dione (CAS 24050-49-5)
- 2-(Bromomethyl)-6-cyano-4-(difluoromethyl)pyridine-3-methanol (CAS 1807126-49-3)
- Methyl 2-bromo-4,5-dihydroxy-3-methoxybenzoate (CAS 848772-95-2)
- [3,4'-Bipyridine]-6-carboxylic acid (CAS 1214363-66-2)
- 2-Chloro-4-methylphenyl isothiocyanate (CAS 57878-93-0)
- 4-(Azetidin-3-yl)-4H-1,2,4-triazole (CAS 1495939-85-9)
- 1-Cyclopropoxy-3-fluoro-5-iodobenzene (CAS 1243322-01-1)
- 3-(Trifluoromethyl)quinoline-2-carbonitrile (CAS 25199-88-6)
- 3-(2-Phenyl-indol-1-yl)-propionic acid 3-(2-phenyl-1H-indol-1-yl)propanoic acid 65746-55-6 (CAS 65746-55-6)
- 2-[1-(dimethylamino)cyclopentyl]acetic acid hydrochloride (CAS 1803584-23-7)
- 2,2,2-Trifluoroethyl 2-(morpholin-4-ylmethyl)pyrrolidine-1-carboxylate (CAS 1306605-24-2)
- (2R,3R,4S,5R)-2-(6-Amino-8-methyl-2-(methylthio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 65991-09-5)
- Galanin (1-13)-Neuropeptide Y (25-36) amide (CAS 147138-51-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com