Dotinurad Impurity 207 CAS 93236-60-3
| CAS No. | 93236-60-3 |
| Molecular Formula | C7H3Cl3O3 |
| Molecular Weight | 241.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Dotinurad Impurity 207 (C7H3Cl3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Dotinurad Impurity 207 (CAS 93236-60-3), a pharmacopoeial impurity reference standard (molecular formula C7H3Cl3O3, MW 241.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3Cl3O3 |
| Molecular Weight | 241.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
Related Dotinurad Standards
- Dotinurad Impurity 54 (CAS CATO-C4X-249454)
- Dotinurad Impurity 63 (CAS CATO-C4X-249463)
- Dotinurad Impurity 115 (CAS CATO-C4X-2494115)
- Dotinurad Impurity 117 (CAS CATO-C4X-2494117)
- Dotinurad Impurity 118 (CAS 127817-86-1)
- Dotinurad Impurity 144 (CAS 74953-20-1)
- Dotinurad Impurity 183 (CAS CATO-C4X-2494183)
- Dotinurad Impurity 179 (CAS CATO-C4X-2494179)
Recommended Standards
- 2-(Bromomethyl)-3-chloro-1,4-difluorobenzene 2-(bromomethyl)-3-chloro-1,4-difluorobenzene, alpha-bromo-2-chloro-3,6-difluorotoluene 2-chloro-3,6-difluorobenzyl bromide 2-chloro-3,6-difluorobenzyl bromide 97% 90292-67-4 alpha-bromo-2-chloro-3,6-difluorotoluene chloro-3,6-difluorobenzylbr currency-bromo-2-chloro-3,6-difluorotoluene (CAS 90292-67-4)
- N,N-dimethyltetradecan-1-amine (CAS 112-75-4)
- Methyl 2,5,6-Trichloropyrimidine-4-carboxylate (CAS 89284-85-5)
- Hexadecylamine (CAS 143-27-1)
- Nafamostat Impurity 60 dimesylate (CAS CATO-C4X-133272)
- Dexamethasone Impurity 98 (CAS CATO-C4X-116598)
- Vildagliptin Impurity 49 (CAS CATO-C4X-110049)
- Cyproterone Impurity 19 (CAS CATO-C4X-16019)
- tert-Butyl 3,3-difluoro-4-(2,2,2-trifluoroacetamido)piperidine-1-carboxylate (CAS 1823836-00-5)
- 3-(1H-Tetrazol-5-yl)piperidine (CAS 112626-96-7)
- Methyltetrazine-PEG4-maleimide (CAS 1802908-02-6)
- N,N-dibenzyl-5-bromothiophene-2-sulfonamide (CAS 618392-59-9)
- Bromo(4-chloro-2-fluorobenzyl)triphenylphosphorane (CAS 101160-85-4)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
Why CATO?
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