1-Chloro-2-(difluoromethyl)-5-fluoro-4-nitrobenzene CAS 932375-23-0
| CAS No. | 932375-23-0 |
| Molecular Formula | C7H3ClF3NO2 |
| Molecular Weight | 225.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Chloro-2-(difluoromethyl)-5-fluoro-4-nitrobenzene (CAS 932375-23-0) is a high-purity analytical reference standard with the molecular formula C7H3ClF3NO2 and a molecular weight of 225.55 g/mol.
1-Chloro-2-(difluoromethyl)-5-fluoro-4-nitrobenzene (C7H3ClF3NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3ClF3NO2 |
| Molecular Weight | 225.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-(trifluoromethyl)nicotinic acid (CAS 1018678-39-1)
- 4-Chloro-6-(trifluoromethyl)picolinic acid (CAS 1060810-65-2)
- 4-chloro-6-(trifluoromethyl)nicotinic acid (CAS 1060810-66-3)
- 6-Chloro-5-(trifluoromethyl)nicotinic Acid (CAS 1110782-41-6)
- 5-Chloro-2-nitrobenzotrifluoride (CAS 118-83-2)
- 5-Chloro-3-(trifluoromethyl)picolinic acid (CAS 1198475-43-2)
- 4-Chloro-5-(trifluoromethyl)nicotinic Acid (CAS 1211520-84-1)
- 4-Chloro-5-(trifluoromethyl)picolinic acid (CAS 1211591-26-2)
Recommended Standards
- 1-(bromomethyl)-3-chloro-2-methylbenzene (CAS 90369-76-9)
- 1-Chloro-3-nitro-5-(trifluoromethyl)benzene (CAS 401-93-4)
- 2-(Difluoromethyl)-3-fluoro-4-hydroxypyridine-6-carbonyl chloride (CAS 1807137-05-8)
- 2-Chloro-1-nitro-3-(trifluoromethyl)benzene (CAS 39974-35-1)
- tert-Butyl ((1R,2R)-2-((tert-butyldimethylsilyl)oxy)-4-hydroxycyclopentyl)carbamate (CAS 2731012-82-9)
- 2-Amino-4-bromo-3,6-difluorobenzoic acid (CAS 1698535-33-9)
- 2-(Aminomethyl)-4-(difluoromethyl)pyridine-5-sulfonyl chloride (CAS 1805304-18-0)
- 2-Chloro-4-fluoropyrimidine (CAS 38953-29-6)
- N-((5-Methyl-1,3,4-oxadiazol-2-yl)methyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamide (CAS 1240264-37-2)
- CAS 67805-34-9 (CAS 67805-34-9)
- 2-Chloro-6-methoxybenzo[d]thiazol-4-amine (CAS 1190321-02-8)
- Nitisinone-13C6 (CAS 1246815-63-3)
- Eriodictyol (CAS 552-58-9)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com