(S)-2-((tert-Butoxycarbonyl)amino)-3,3,3-trifluoropropanoic acid CAS 932644-89-7
| CAS No. | 932644-89-7 |
| Molecular Formula | C8H12F3NO4 |
| Molecular Weight | 243.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(S)-2-((tert-Butoxycarbonyl)amino)-3,3,3-trifluoropropanoic acid (CAS 932644-89-7) is a high-purity analytical reference standard with the molecular formula C8H12F3NO4 and a molecular weight of 243.18 g/mol.
The molecular framework of (S)-2-((tert-Butoxycarbonyl)amino)-3,3,3-trifluoropropanoic acid (C8H12F3NO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H12F3NO4 |
| Molecular Weight | 243.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (3-(4-(Trifluoromethyl)phenyl)isoxazol-5-yl)methanol (CAS 206055-88-1)
- (S)-4,4,4-Trifluoro-2-((methoxycarbonyl)amino)-3,3-dimethylbutanoic acid (CAS 2242426-54-4)
- 2-(Boc-amino)-3,3,3-trifluoropropanoic Acid (CAS 188030-43-5)
- [2-(3,5-Dioxo-2,3,4,5-tetrahydro-[1,2,4]triazin-6-ylamino)-acetylamino]-acetic acid (CAS 333432-84-1)
- 3-Chloro-N-(4-fluorobenzyl)aniline (CAS 1019540-88-5)
- 3-(3,4-Difluorophenyl)prop-2-yn-1-ol (CAS 893747-16-5)
- 3-(2-Fluorophenyl)-1-(furan-3-ylmethyl)-1-(2-methoxyethyl)urea (CAS 1421504-77-9)
- N-(2-Fluorobenzylidene)-2-methylpropan-2-amine (CAS 195004-63-8)
- 3-carbamoyl-5-(chlorosulfonyl)benzoic acid (CAS 1099186-87-4)
- n-(1-(4-Methoxyphenyl)propyl)cyclopropanamine (CAS 926202-13-3)
- 2-(Methoxymethyl)phenol (CAS 5635-98-3)
- 5-Fluoro-2-(1-p-tolyl-1H-pyrazol-5-yl)phenol (CAS 876950-48-0)
- (S)-1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine (CAS 791758-82-2)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com