5-Ethynyl-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one CAS 93265-82-8
| CAS No. | 93265-82-8 |
| Molecular Formula | C11H12N2O4 |
| Molecular Weight | 236.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Ethynyl-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (CAS 93265-82-8) is a high-purity analytical reference standard with the molecular formula C11H12N2O4 and a molecular weight of 236.22 g/mol.
The molecular framework of 5-Ethynyl-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (C11H12N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Ethynyl-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12N2O4 |
| Molecular Weight | 236.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Nitrogen Atoms | 2 |
Related Ethynyl Standards
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Recommended Standards
- 5-[3,4-(Methylenedioxy)phenyl]-5-oxovaleric acid (CAS 87961-41-9)
- 5-Methoxy-3-(2-methoxy-5-methylphenyl)-1,3,4-oxadiazol-2(3H)-one (CAS 98414-86-9)
- 5,7,8-Trimethoxycoumarin (CAS 60796-65-8)
- 6,7-Dimethoxy-3-methylbenzofuran-2-carboxylic acid (CAS 63445-53-4)
- Dimethyl(trifluoroacetylacetonate)gold(III) (CAS 63470-53-1)
- 6-Acrylamido-N-cyclohexylhexanamide (CAS 606933-07-7)
- Octafluoroadipoyl difluoride (CAS 37881-62-2)
- 2-Bromo-3,5-diiodopyridine (CAS 885952-14-7)
- (2R,6R)-2,6-Dimethyl-1,3-dioxan-4-one (CAS 100017-17-2)
- 6-Amino-1-(3-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde (CAS 910443-02-6)
- 2-((Cyclohexylmethyl)amino)butan-1-ol (CAS 932005-24-8)
- 5-(Furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride (CAS 848422-53-7)
- Ebastine Impurity 14 (CAS CATO-C4X-202914)
- Gastrin Tetrapeptide (CAS 1947-37-1)
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