1-Ethynyl-2,4-bis(trifluoromethyl)benzene CAS 88444-79-5
| CAS No. | 88444-79-5 |
| Molecular Formula | C10H4F6 |
| Molecular Weight | 238.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 238.13 g/mol gives 1-Ethynyl-2,4-bis(trifluoromethyl)benzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-Ethynyl-2,4-bis(trifluoromethyl)benzene (CAS 88444-79-5), a certified reference material (molecular formula C10H4F6, MW 238.13 g/mol) for analytical method development and quality control.
1-Ethynyl-2,4-bis(trifluoromethyl)benzene (C10H4F6) contains fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H4F6 |
| Molecular Weight | 238.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F-containing |
Related Ethynyl Standards
- 2-Ethynyl-1,4-bis(trifluoromethyl)benzene (CAS 88444-78-4)
- 1-Ethynyl-2-((4-methoxyphenoxy)methyl)benzene (CAS 1160063-52-4)
- 1-Ethynyl-1-(triisopropylsilyloxy)cyclopropane 1246814-98-1 (CAS 1246814-98-1)
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Recommended Standards
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- (3AS,4S,6S,7aR)-2-isopropoxy-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole (CAS 819816-59-6)
- 2-(2,6-Dimethyl-3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246427-45-0)
- 1-(3-(Trifluoromethoxy)benzyl)piperazine (CAS 868054-25-5)
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