2,3,5-Trichlorophenol CAS 933-78-8
| CAS No. | 933-78-8 |
| Molecular Formula | C6H3Cl3O |
| Molecular Weight | 197.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,3,5-Trichlorophenol is closely related to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,3,5-Trichlorophenol (CAS 933-78-8), molecular formula C6H3Cl3O and molecular weight 197.45 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,3,5-Trichlorophenol (C6H3Cl3O) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,3,5-Trichlorophenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3Cl3O |
| Molecular Weight | 197.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Trichlorophenol Standards
- 2,3,4-Trichlorophenol (CAS 15950-66-0)
- 2,3,6-Trichlorophenol (CAS 933-75-5)
- 2,4,5-Trichlorophenol (CAS 95-95-4)
- 2,4,6-Trichlorophenol (CAS 88-06-2)
- 3,4,5-Trichlorophenol (CAS 609-19-8)
- 2,3,5-Trichlorophenol-4,6-d (CAS 358730-84-4)
- 2,3,6-Trichlorophenol-4,5-d2 (CAS 93951-81-6)
- 2,4,5-Trichlorophenol-3,6-d2 (CAS 93951-82-7)
Recommended Standards
- 2,3,5-Trichloropyridin-4-amine (CAS 28443-69-8)
- Dasatinib Impurity 49 (CAS 54198-86-6)
- 4,6-Dichloro-2-(chloromethyl)pyrimidine (CAS 19875-05-9)
- 3,4,6-Trichloro-5-methylpyridazine (CAS 499235-55-1)
- N1-benzyl-N2-phenylethane-1,2-diamine (CAS 58077-34-2)
- (6-Amino-5-bromo-3-(difluoromethyl)pyridin-2-yl)methanol (CAS 1806812-93-0)
- 1-Boc-2-(chloromethyl)benzimidazole (CAS 163798-87-6)
- 6-chloro-1H-thieno[2,3-d]pyrimidine-2,4-dione (CAS 2659313-22-9)
- 6-(Benzyloxy)-1H-indazol-5-amine (CAS 1499162-36-5)
- 4-Iodo-N-methylaniline hydrochloride (CAS 84250-74-8)
- (1R,2R)-Methyl 1-amino-2-ethylcyclopropanecarboxylate (CAS 772326-49-5)
- pramipexole Impurity 31 (CAS CATO-C4X-110731)
- 1,1,1-Trifluoro-3-[(2-hydroxy-1-phenylethyl)amino]propan-2-ol (CAS 477889-78-4)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com