Dasatinib Impurity 49 CAS 54198-86-6
| CAS No. | 54198-86-6 |
| Molecular Formula | C5H3Cl3N2 |
| Molecular Weight | 197.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 197.45 g/mol gives Dasatinib Impurity 49 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Dasatinib Impurity 49 (CAS 54198-86-6), a pharmacopoeial impurity reference standard (molecular formula C5H3Cl3N2, MW 197.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C5H3Cl3N2, Dasatinib Impurity 49 contains a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 197.45 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H3Cl3N2 |
| Molecular Weight | 197.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dasatinib Standards
- Dasatinib Impurity O (CAS 53848-17-2)
- Dasatinib Impurity 10 (CAS 30273-00-8)
- Dasatinib Impurity 12 (CAS 62077-27-4)
- Dasatinib Impurity 17 (CAS 62077-26-3)
- Dasatinib Impurity 50 (CAS 1935225-16-3)
- Dasatinib Impurity 42 (CAS 1780-26-3)
- Dasatinib Impurity 44 (CAS 1184914-03-1)
- Dasatinib Impurity 18 (CAS CATO-C4X-160718)
Recommended Standards
- 4,6-Dichloro-2-(chloromethyl)pyrimidine (CAS 19875-05-9)
- 2,3,5-Trichloropyridin-4-amine (CAS 28443-69-8)
- 3,4,6-Trichloro-5-methylpyridazine (CAS 499235-55-1)
- 2,3,4-Trichlorophenol (CAS 15950-66-0)
- Chlorphenamine Impurity 46 (CAS CATO-C4X-118846)
- Mesna EP Impurity B (CAS 1391053-66-9)
- Ticagrelor Impurity 183 (CAS CATO-C4X-1093183)
- des-3-D-3Pal-Cetrorelix (CAS CATO-C4X-201460)
- Dopamine Impurity 62 (CAS CATO-C4X-190862)
- Methyl 1H-pyrrolo[2,3-c]pyridine-3-carboxylate (CAS 108128-12-7)
- Carbidopa impurity 38 (CAS 2470439-16-6)
- 2-[(4-Nitrophenyl)carbamoyl]thiophen-3-yl N,N-dimethylsulfamate (CAS 338794-40-4)
- 3-Bromo-5-cyclopropoxy-N-methylisonicotinamide (CAS 1243281-98-2)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com