(2,4-Dichloropyrimidin-5-yl)methanamine CAS 933685-97-3
| CAS No. | 933685-97-3 |
| Molecular Formula | C5H5Cl2N3 |
| Molecular Weight | 178.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (2,4-Dichloropyrimidin-5-yl)methanamine (CAS 933685-97-3), a certified reference material (molecular formula C5H5Cl2N3, MW 178.02 g/mol) for analytical method development and quality control.
The molecular framework of (2,4-Dichloropyrimidin-5-yl)methanamine (C5H5Cl2N3) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2,4-Dichloropyrimidin-5-yl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H5Cl2N3 |
| Molecular Weight | 178.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloropyrimidin Standards
- (4,6-Dichloropyrimidin-2-yl)methanamine (CAS 933720-62-8)
- (4,6-Dichloropyrimidin-2-yl)methanol (CAS 1244949-68-5)
- (2,4-Dichloropyrimidin-5-yl)methanol (CAS 1346537-23-2)
- (2,6-dichloropyrimidin-4-yl)methanol (CAS 321329-01-5)
- 2-(2,4-Dichloropyrimidin-5-yl)acetonitrile (CAS 1000548-88-8)
- 2-(2,6-Dichloropyrimidin-4-yl)acetonitrile (CAS 19785-42-3)
- 1-(2,4-Dichloropyrimidin-5-yl)ethanone (CAS 871254-62-5)
- 2,4-Dichloropyrimidin-5-ol (CAS 1395037-19-0)
Recommended Standards
- (2,3-Dichloro-4-pyridinyl)methanol (CAS 329794-25-4)
- (2,5-Dichloropyridin-3-yl)methanol (CAS 558465-93-3)
- 3,4-Dichloro-1-methylpyridin-2(1H)-one (CAS 1956324-42-7)
- (3,5-Dichloropyridin-2-yl)methanol (CAS 275383-87-4)
- 3-(3-Chlorophenyl)-5-((3-methoxybenzyl)thio)-4H-1,2,4-triazol-4-amine (CAS 573947-81-6)
- 3-((4-Fluorophenyl)amino)-1-(3-nitrophenyl)propan-1-one (CAS 350039-84-8)
- 3-Methyl-4-nitrobenzenediazonium Tetrafluoroborate (CAS 24964-88-3)
- 5H-Cyclopenta[d]pyrazolo[1,5-a]pyrimidin-8-ol, 3-bromo-6,7-dihydro- (CAS 1310249-56-9)
- tert-Butyl 3-(aminomethyl)-4-fluoropiperidine-1-carboxylate (CAS 1303973-02-5)
- (3-((tert-Butoxycarbonyl)amino)-4-methylphenyl)boronic acid (CAS 850568-81-9)
- tert-Butyl (4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl)carbamate (CAS 2041076-40-6)
- 2-{4-[(2,5-dioxoimidazolidin-4-yl)methyl]-1H-1,2,3-triazol-1-yl}acetic acid hydrochloride (CAS 1786226-08-1)
- Ethyl 5-amino-4-iodo-1-phenyl-1H-pyrazole-3-carboxylate (CAS 1427011-93-5)
- Gastric Inhibitory Polypeptide (3-42) (human) trifluoroacetate salt (CAS 1802086-25-4)
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