(6-Chloro-2-pyridinyl)methanol CAS 33674-97-4
| CAS No. | 33674-97-4 |
| Molecular Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (6-Chloro-2-pyridinyl)methanol.
(6-Chloro-2-pyridinyl)methanol (CAS 33674-97-4), molecular formula C6H6ClNO and molecular weight 143.57 g/mol, is a CATO reference standard with documented purity and traceability.
(6-Chloro-2-pyridinyl)methanol (C6H6ClNO) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (6-Chloro-2-pyridinyl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-6-methylpyridin-2-ol (CAS 103997-23-5)
- N-(3-Chloro-phenyl)hydroxylamine (CAS 10468-17-4)
- (5-Chloro pyrazin-2-yl) Methanamine (CAS 1060814-53-0)
- 4-Chloro-3-methylpyridine 1-Oxide (CAS 1073-34-3)
- 2-Chloro-3-hydrazinylpyridine (CAS 117087-45-3)
- 5-Chloro-2-methylpyridin-4(1H)-one (CAS 1196157-19-3)
- 2-Chloro-1-(1H-pyrrol-3-yl)ethanone (CAS 122450-28-6)
- 3-Chloro-2-methylpyridin-4-ol (CAS 1227499-23-1)
Recommended Standards
- (4-Chloropyrimidin-2-yl)methanamine (CAS 944902-16-3)
- (6-chloropyridazin-3-yl)methanamine (CAS 871826-15-2)
- (3-Chloropyridin-2-yl)methanol (CAS 60588-81-0)
- (6-Chloropyrimidin-4-yl)methanamine (CAS 933702-18-2)
- 2-(azidomethyl)benzoic acid (CAS 289712-57-8)
- 1-(3-Fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-carbothioamide (CAS 1019187-19-9)
- rel-3-(tert-Butyl) 4-methyl (2S,4R)-2-hydroxythiazolidine-3,4-dicarboxylate (CAS 1140832-56-9)
- 5-(4-Chlorophenyl)-N,N-dimethyl-1,3,4-oxadiazol-2-amine (CAS 4469-02-7)
- 2-(4-Hydroxy-6-(phenylthio)isoquinoline-3-carboxamido)acetic acid (CAS 808116-39-4)
- tert-Butyl (S)-2-methyl-4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)pyrrolidine-1-carboxylate (CAS 2879335-01-8)
- (R)-2-(2-Bromophenyl)piperazine (CAS 1213194-15-0)
- 4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-2(1H)-one (CAS 29868-19-7)
- 1-(O-tolyl)prop-2-en-1-ol (CAS 39627-62-8)
- Fragment-[7-31]-Liraglutide (CAS CATO-C4X-199239)
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