Omeprazole impurity 35 CAS 933730-07-5
| CAS No. | 933730-07-5 |
| Molecular Formula | C8H7BrN2O |
| Molecular Weight | 227.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 227.06 g/mol gives Omeprazole impurity 35 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Omeprazole impurity 35 (CAS 933730-07-5), a pharmacopoeial impurity reference standard (molecular formula C8H7BrN2O, MW 227.06 g/mol) used for the identification and quantification of trace impurities in APIs.
Omeprazole impurity 35 (C8H7BrN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7BrN2O |
| Molecular Weight | 227.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Omeprazole Standards
- Omeprazole Impurity 59 (CAS 106135-28-8)
- Omeprazole Impurity 6 (CAS CATO-C4X-12556)
- Omeprazole Impurity 54 (CAS 23165-60-8)
- Omeprazole Impurity 64 (CAS 50651-39-3)
- Omeprazole Impurity 19 (CAS 119-81-3)
- Omeprazole Impurity 20 (CAS CATO-C4X-125520)
- Omeprazole Impurity 54 (CAS 187222-18-0)
- Omeprazole N1-Methyl 6-Methoxy Thiol Impurity (CAS 1526768-06-8)
Recommended Standards
- 8-Bromo-7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-amine (CAS 2413985-26-7)
- 2,4-Dichloro-6-(methylsulfonyl)pyrimidine (CAS 1048389-45-2)
- 8-Bromo-3,4-dihydro-1,6-naphthyridin-2(1H)-one (CAS 885271-02-3)
- 2,6-Dichloropyridine-3-sulfonamide (CAS 1078627-77-6)
- N-Nitroso Buspirone EP Impurity A (CAS 872826-80-7)
- Bedaquiline Impurity 62 (CAS CATO-C4X-116762)
- Abiraterone Impurity 49 (CAS CATO-C4X-107049)
- Tert-butyl (2-(3-fluorophenyl)propan-2-yl)carbamate (CAS 689232-63-1)
- 1-(1,2-Dimethyl-1h-indol-3-yl)-2,2,2-trifluoroethan-1-ol (CAS 883802-40-2)
- S-isopropyl-L-cysteine (CAS 5443-40-3)
- Methyl 2-(2-((tert-butoxycarbonyl)amino)ethyl)oxazole-4-carboxylate (CAS 871726-03-3)
- 2-Bromo-1H-benzo[d]imidazole-5-carbonitrile (CAS 1388069-26-8)
- tert-Butyl 3-fluoro-3-(pyridin-3-yl)pyrrolidine-1-carboxylate (CAS 1225218-41-6)
- Tau Peptide (275-305) (Repeat 2 Domain) trifluoroacetate salt (CAS 330456-25-2)
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