Omeprazole Impurity 54 CAS 187222-18-0
| CAS No. | 187222-18-0 |
| Molecular Formula | C10H13NO3 |
| Molecular Weight | 195.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Omeprazole Impurity 54 (C10H13NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Omeprazole Impurity 54 (CAS 187222-18-0) is a certified pharmaceutical impurity reference standard with the molecular formula C10H13NO3 and a molecular weight of 195.22 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Omeprazole Impurity 54 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13NO3 |
| Molecular Weight | 195.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Nitrogen Atoms | 1 |
Related Omeprazole Standards
- Omeprazole N1-Methyl 6-Methoxy Thiol Impurity (CAS 1526768-06-8)
- Omeprazole Impurity 20 (CAS CATO-C4X-125520)
- Omeprazole Impurity 24 (CAS 109371-17-7)
- Omeprazole Impurity 36 (CAS CATO-C4X-125536)
- Omeprazole Impurity 23 (CAS 105602-84-4)
- Omeprazole Impurity 60 (CAS 150054-47-0)
- Omeprazole Impurity 49 (CAS 22094-69-5)
- Omeprazole Impurity 55 (CAS 58469-06-0)
Recommended Standards
- Rivaroxaban Impurity 97 (CAS 2288308-42-7)
- Ilaprazole Impurity 75 (CAS 102625-98-9)
- Rivaroxaban Impurity 96 (CAS 1007650-38-5)
- Lenvatinib Impurity 115 (CAS 106868-33-1)
- Iopromide Impurity 9 (CAS 111453-32-8)
- Urapidil Impurity 58 (CAS CATO-C4X-192458)
- Canagliflozin Impurity 42 (CAS CATO-C4X-112342)
- 1-(2-chlorophenyl)-4-methyl-1H-pyrazol-3-amine (CAS 1249384-77-7)
- Diclofenac potassium (CAS 15307-81-0)
- 5-(3-Hydroxy-4-methoxybenzylidene)imidazolidine-2,4-dione (CAS 4368-00-7)
- Adropin (34-76) (human, mouse, rat) trifluoroacetate salt (CAS 1802086-30-1)
- 2-Chloro-1-(1,5-dimethyl-1H-pyrrol-2-yl)ethan-1-one (CAS 88098-22-0)
- Cyclohexane-1,3-diamine dihydrochloride (CAS 28294-92-0)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
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