Venlafaxine EP Impurity E HCl CAS 93413-56-0
| CAS No. | 93413-56-0 |
| Molecular Formula | C17H25NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Venlafaxine EP Impurity E HCl (CAS 93413-56-0) is a certified pharmaceutical impurity reference standard with the molecular formula C17H25NO2HCl and a molecular weight of 311.85 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Venlafaxine EP Impurity E HCl is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 311.85 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Venlafaxine EP Impurity E HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H25NO2 HCl |
| Molecular Weight | 311.85 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Venlafaxine Standards
- Venlafaxine Impurity 58 (CAS 1000377-27-4)
- Venlafaxine Impurity 31 (CAS 1020719-35-0)
- Venlafaxine Impurity 15 (CAS 1021933-95-8)
- Venlafaxine Impurity 33 (CAS 1062607-49-1)
- Venlafaxine Impurity 36 (CAS 1062609-99-7)
- Venlafaxine EP Impurity G (CAS 1076199-92-2)
- Venlafaxine N-Oxide (CAS 1094598-37-4)
- Venlafaxine Impurity 18 (CAS 1168135-16-7)
Recommended Standards
- Vonoprazan Impurity 232 (CAS CATO-C4X-1020232)
- Sotagliflozin Impurity 2 (CAS 1327165-94-5)
- Bumetanide Impurity 35 (CAS CATO-C4X-198635)
- Dimethyl 2,5-dibromothiophene-3,4-dicarboxylate (CAS 937640-21-6)
- 4-Acetoxy Midazolam (1.0mg/ml in Acetonitrile) (CAS 59468-84-7)
- 2-(Thiophen-2-yl)-1,3-benzoxazol-5-amine (CAS 52331-74-5)
- 1-Isopropyl-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea (CAS 874299-06-6)
- tert-Butyl (3-Amino-1-phenylpropyl)carbamate (CAS 883510-34-7)
- 2-((5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(m-tolyl)acetamide (CAS 332114-25-7)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
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