4-Acetoxy Midazolam (1.0mg/ml in Acetonitrile) CAS 59468-84-7
| CAS No. | 59468-84-7 |
| Molecular Formula | C20H15ClFN3O2 |
| Molecular Weight | 383.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Acetoxy Midazolam (1.0mg/ml in Acetonitrile) (C20H15ClFN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-Acetoxy Midazolam (1.0mg/ml in Acetonitrile) (CAS 59468-84-7), molecular formula C20H15ClFN3O2 and molecular weight 383.80 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Acetoxy Midazolam (1.0mg/ml in Acetonitrile) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H15ClFN3O2 |
| Molecular Weight | 383.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Acetoxy Standards
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Recommended Standards
- 2-Chloro-4-formyl-6-methoxyphenyl 4-acetamidobenzenesulfonate (CAS 432002-40-9)
- 6-Chloro-4-((4-methoxyphenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid (CAS 866134-61-4)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2,4,5-trifluorophenyl)acetamide (CAS 303091-66-9)
- 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-α][1,4]benzodiazepine-3-carboxylic Acid Methyl Ester (CAS 59468-42-7)
- N-(benzo[d][1,3]dioxol-5-yl)-4-(3-phenylallyl)piperazine-1-carboxamide (CAS 1164513-65-8)
- (E)-3-chloro-2-(2-(4-chlorobenzylidene)hydrazinyl)-5-(trifluoromethyl)pyridine (CAS 338795-09-8)
- 5-(5-Methyloxazol-2-yl)pyridin-2-ol (CAS 1255098-69-1)
- 2-(tert-Butoxy)-4-hydroxy-N-methylbenzamide (CAS 1243440-96-1)
- 3-Cyclopropoxy-2-(dimethylamino)-N,N-dimethylbenzamide (CAS 1243467-38-0)
- Chlorhexidine Impurity 31 (CAS CATO-C4X-225631)
- 5-(4-methylpiperidin-1-yl)-1,3,4-thiadiazol-2-amine (CAS 71125-48-9)
- Acotiamide Impurity 30 (CAS CATO-C4X-111430)
- Tert-butyl 3-amino-1-methyl-1H-pyrazole-5-carboxylate (CAS 1379353-30-6)
- Exenatide (CAS 141758-74-9)
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