Terbinafine EP Impurity E CAS 934365-23-8
| CAS No. | 934365-23-8 |
| Molecular Formula | C36H40N2 |
| Molecular Weight | 500.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Terbinafine EP Impurity E.
As a process- or degradation-related impurity, Terbinafine EP Impurity E (CAS 934365-23-8, C36H40N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Terbinafine EP Impurity E (C36H40N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Terbinafine EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C36H40N2 |
| Molecular Weight | 500.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Terbinafine Standards
- Terbinafine Hydroxy β-D-Glucuronide (CAS 99473-12-8)
- Terbinafine Impurity 29 (CAS CATO-C4X-133829)
- Terbinafine Hydroxy Benzoate (CAS 1076198-30-5)
- Terbinafine Carboxylic Acid Methyl Ester (Oxalate) (CAS 1076199-76-2)
- Terbinafine EP Impurity F (CAS 926281-74-5)
- Terbinafine Impurity 6 (CAS 99473-14-0)
- Terbinafine Impurity 5-d7 (CAS 1185238-58-7)
- Terbinafine Impurity 1 (CAS 134274-69-4)
Recommended Standards
- 2,9-Bis(2,4,6-triethylphenyl)-1,10-phenanthroline (CAS 2173362-84-8)
- Lurasidone-d8 (CAS 1132654-54-6)
- 4,4'-(4,4-Diphenylbuta-1,3-diene-1,1-diyl)bis(N,N-diethylaniline) (CAS 109995-82-6)
- Arotinolol Impurity 40 (CAS CATO-C4X-185440)
- Docetaxel Impurity 32 (CAS 1112457-40-5)
- Procaterol Impurity N7 (CAS 15450-72-3)
- Arbidol Impurity 57 (CAS CATO-C4X-112957)
- 6-Methoxy-1-methyl-3,4-dihydroquinolin-2(1H)-one (CAS 187679-62-5)
- (Iminomethyl)-L-aspartic acid (CAS 2374-41-6)
- 4-((4-Oxothiazolidin-2-ylidene)amino)benzoic acid (CAS 82365-56-8)
- 1-{[4-Chloro-3-(trifluoromethyl)phenyl]methyl}-2-methylpiperazine (CAS 1240573-35-6)
- Ethyl 4-chloro-3-methylbenzoylformate (CAS 250642-57-0)
- Phenyl Isothiocyanate (CAS 103-72-0)
- Lixisenatide (CAS 320367-13-3（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com