Desoximetasone Impurity 5 CAS 4306-57-4

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.4306-57-4
Molecular FormulaC22H29ClO4
Molecular Weight392.92 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Desoximetasone Impurity 5 CAS 4306-57-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 392.92 g/mol gives Desoximetasone Impurity 5 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Desoximetasone Impurity 5 (CAS 4306-57-4), a pharmacopoeial impurity reference standard (molecular formula C22H29ClO4, MW 392.92 g/mol) used for the identification and quantification of trace impurities in APIs.

Desoximetasone Impurity 5 (C22H29ClO4) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Desoximetasone Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC22H29ClO4
Molecular Weight392.92 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Halogen ContentCl-containing

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