3-Fluorophenylboronic Acid Pinacol Ester CAS 936618-92-7
| CAS No. | 936618-92-7 |
| Molecular Formula | C12H16BFO2 |
| Molecular Weight | 222.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 222.06 g/mol gives 3-Fluorophenylboronic Acid Pinacol Ester distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Fluorophenylboronic Acid Pinacol Ester (CAS 936618-92-7) is a high-purity analytical reference standard with the molecular formula C12H16BFO2 and a molecular weight of 222.06 g/mol.
The molecular framework of 3-Fluorophenylboronic Acid Pinacol Ester (C12H16BFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16BFO2 |
| Molecular Weight | 222.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Fluorophenylboronic Standards
- 4-Fluorophenylboronic Acid Pinacol Ester (CAS 214360-58-4)
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- 5-Acetyl-2-fluorophenylboronic Acid (CAS 870777-29-0)
- 4-Fluorophenylboronic acid N-butyldiethanolamine ester (CAS 1190988-96-5)
- 3-Ethyl-4-fluorophenylboronic acid (CAS 960235-01-2)
- 4-Fluorophenylboronic acid (CAS 1765-93-1)
- 4-fluorophenylboronic anhydride (CAS 448-59-9)
Recommended Standards
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- 4-Bromo-3-methyl-1,2-thiazole-5-carboxylic acid (CAS 89284-01-5)
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- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
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