4-chloro-6-(2-methoxyethoxy)quinazoline CAS 937263-67-7
| CAS No. | 937263-67-7 |
| Molecular Formula | C11H21ClN2O2 |
| Molecular Weight | 248.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-chloro-6-(2-methoxyethoxy)quinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-chloro-6-(2-methoxyethoxy)quinazoline (CAS 937263-67-7), molecular formula C11H21ClN2O2 and molecular weight 248.75 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-chloro-6-(2-methoxyethoxy)quinazoline (C11H21ClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 248.75 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H21ClN2O2 |
| Molecular Weight | 248.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
- 7-chloro-N-(3-methylbutan-2-yl)quinolin-4-amine (CAS 1039979-35-5)
- N-(2-Chloro-6-(hydroxymethyl)pyridin-3-yl)pivalamide (CAS 1142191-92-1)
- 4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-carbaldehyde (CAS 1202186-71-7)
- 2-Chloro-N-(3-(2,6-dimethylmorpholino)propyl)acetamide (CAS 1208957-38-3)
- 7-Chloro-N-(2,2-dimethylpropyl)quinolin-4-amine (CAS 1284968-35-9)
- 6-chloro-N-ethyl-2,3,4,9-tetrahydro-1H-carbazol-3-amine (CAS 1432679-41-8)
- 2-Chloro-5,5,7,7-tetramethyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 1919633-72-9)
- 2-Chloro-n-{[4-(2-methylpropyl)morpholin-2-yl]methyl}acetamide (CAS 848369-66-4)
Recommended Standards
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- 2-Hydroxy-5-[(2-methoxyphenyl)sulfamoyl]benzoic acid (CAS 262282-50-8)
- cyclohexylhydrazine (CAS 6498-34-6)
- 4-((2-Chloro-4-nitrophenoxy)methyl)benzoic acid (CAS 30880-70-7)
- (6,7,8,9-Tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-9-yl)methanamine (CAS 1707568-29-3)
- n-(Sec-butyl)-3-isopropyl-1,2,4-oxadiazol-5-amine (CAS 1259058-67-7)
- 2-(Pyrazin-2-yl)-1,3-thiazole-4-carboxylic acid (CAS 115311-44-9)
- N-(4-(Benzofuran-2-yl)thiazol-2-yl)-5-chlorothiophene-2-carboxamide (CAS 716365-80-9)
- N,N-dimethyl-4-((3-(trifluoromethyl)pyridin-2-yl)oxy)benzenesulfonamide (CAS 1257535-14-0)
- 3,3＇,5,5＇-Tetra-tert-butyl-2,2＇-dihydroxybiphenyl (CAS 6390-69-8)
- Tirzepatide Impurity 14 (CAS CATO-C4X-324014)
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