N-(2-Chloro-6-(hydroxymethyl)pyridin-3-yl)pivalamide CAS 1142191-92-1
| CAS No. | 1142191-92-1 |
| Molecular Formula | C11H21ClN2O2 |
| Molecular Weight | 248.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies N-(2-Chloro-6-(hydroxymethyl)pyridin-3-yl)pivalamide (CAS 1142191-92-1), a certified reference material (molecular formula C11H21ClN2O2, MW 248.75 g/mol) for analytical method development and quality control.
Structurally, N-(2-Chloro-6-(hydroxymethyl)pyridin-3-yl)pivalamide (C11H21ClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 248.75 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H21ClN2O2 |
| Molecular Weight | 248.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- Pitolisant impurity 20 (CAS CATO-C4X-252020)
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- 1-Methyl-1H-pyrazolo[4,3-e][1,2,4]triazin-3(2H)-one (CAS 888490-32-2)
- 6-Chloro-3-(3,4-dihydro-2H-pyrrol-5-yl)-2-methylpyridine (CAS 1352490-29-9)
- 2-methyl-1-phenylpyrrolidine-3-carboxylic acid (CAS 1797567-32-8)
- 7,8-Dihydro-5H-pyrano[4,3-b]pyridine-2,3-diamine (CAS 1260670-87-8)
- (s)-fmoc-2-amino-3-propargyloxy-propionic acid 1354752-75-2 (CAS 1354752-75-2)
- 3-((2-(Trifluoromethyl)pyrimidin-4-yl)oxy)benzaldehyde (CAS 1086379-00-1)
- 2-Fluoro-4'-(trifluoromethyl)biphenyl-3-carboxylic acid (CAS 1261669-11-7)
- Adefovir Impurity 8 (CAS 1416439-02-5)
- 2-(2-(((3-(Benzyloxy)-3-oxopropyl)amino)methyl)piperidin-1-yl)acetic acid (CAS 1353984-72-1)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
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